Uridine-5′-diphosphoglucuronic acid trisodium nnu CAS: 63700-19-6 White ntụ ntụ.
| Nọmba katalọgụ | XD90382 |
| Aha ngwaahịa | Uridine-5'-diphosphoglucuronic acid trisodium nnu |
| CAS | 63700-19-6 |
| Usoro ihe omimi | C15H19N2O18P2Na3 |
| Ibu molekụla | 646.20 |
| Nkọwa nchekwa | <-4 Celsius C |
Nkọwapụta ngwaahịa
| Nyocha | 99% |
| Ọdịdị | Ọcha ntụ ntụ |
Ọmụmụ ihe dị ugbu a na-achọ ịchọpụta mmetụta nke nsi nke irinotecan site na biotransformation nke glucoaurantio-obtusin na aurantio-obtusin.Intraperitoneal nchịkwa (ip) nke 100 mg/kg aurantio-obtusin budata ụbara nsi nke irinotecan, mana nchịkwa ip nke 100 mg/kg glucoaurantion-obtusin gosipụtara mmetụta na-adịghị mma n'ebe toxicity nke irinotecan nọ.Ọzọkwa, a kọwapụtara usoro ahụ site n'ịchọpụta ike mgbochi nke glucoaurantio-obtusin na aurantio-obtusin kwupụta glucuronidation metabolism nke SN-38 nke a na-ewere dị ka isi ihe na-arụsi ọrụ ike nke na-akpata nsị nke irinotecan.Nsonaazụ gosiri na aurantio-obtusin gosipụtara mgbochi asọmpi siri ike maka glucuronidation nke SN-38, mana enwere ike igbochi glucoaurantio-obtusin kwupụta SN-38 glucuronidation.Nsonaazụ ndị a gosiri na biotransformation nke glucoaurantio-obtusin kwupụta aurantio-obtusin mụbara toxicity nke irinotecan site na mmụba nke mgbochi SN-38 glucuronidation.
