Streptavidin sitere na Streptomyces avidinii CAS: 9013-20-1
| Nọmba katalọgụ | XD90329 |
| Aha ngwaahịa | Streptavidin sitere na Streptomyces avidinii |
| CAS | 9013-20-1 |
| Usoro ihe omimi | C14H17BrClNO2S |
| Ibu molekụla | 378.71 |
| Nkọwa nchekwa | -15 ruo -20 Celsius |
| Koodu tarifu akwadoro | 35040090 |
Nkọwapụta ngwaahịa
| Ọdịdị | Ọcha ntụ ntụ |
| Nyocha | 99% |
| Maka iji nyocha naanị, ọ bụghị maka ojiji mmadụ | iji nyocha naanị, ọ bụghị maka mmadụ |
Alkyne-hinged 3-fluorosialyl fluoride (DFSA) nwere otu alkyne ka egosiri na ọ bụ ihe na-egbochi sialidases na-enweghị ike ịgbanwe agbanwe dabere na ebumnuche.Ester-echebe analọg DFSA (PDFSA) bụ membrane-permeable precursor nke DFSA e mere ka a na-eji na ndụ cell, na e gosiri na-etolite covalent adducts na nje, bacteria, na mmadụ sialidases.Enwere ike ijikọ njikọ fluorosialyl-enzyme na biotin azide-agbakwunyere site na mmeghachi omume pịa wee chọpụta ya site na akara mkpesa streptavidin akọwapụtara.Liquid chromatography-mass spectrometry/mass spectrometry analysis na iberibe peptide tryptic na-egosi na 3-fluorosialyl moiety na-agbanwe ihe fọdụrụ tyrosine nke sialidases.Ejiri DFSA iji gosipụta ọrịa influenza na nchọpụta nke viral susceptibility na anti-influenza ọgwụ oseltamivir acid, ebe a na-eji PDFSA mee ihe n'ọnọdụ ọnọdụ nke mgbanwe nke ọrụ sialidase na sel ndụ.
