Cytochrome C CAS: 9007-43-6 ntụ ntụ na-acha ọbara ọbara ma ọ bụ ọchịchịrị gbara ọchịchịrị
| Nọmba katalọgụ | XD90330 |
| Aha ngwaahịa | Cytochrome C |
| CAS | 9007-43-6 |
| Usoro ihe omimi | C42H54FeN8O6S2 |
| Ibu molekụla | 886.91 |
| Nkọwa nchekwa | -15 ruo -20 Celsius |
| Koodu tarifu akwadoro | 35040090 |
Nkọwapụta ngwaahịa
| Ọdịdị | ntụ ntụ na-acha uhie uhie ma ọ bụ ọchịchịrị gbara ọchịchịrị |
| Nyocha | 99% |
| pH | 5-7 |
| Ígwè | 0.40 - 0.48% |
| Ịdị ọcha | Nkeji 90% |
| Ihe fọdụrụ na mgbanye | Kachasị 1.5% |
| Mmiri | Kachasị 6% |
| Ịgba nwa | Na-akwado ule ịmụ nwa |
| Pyrogens | N'efu |
| Ule agba | Nke dị mma |
| E. Coli | Adịghị |
| Ụdị Salmonella | Adịghị |
| Solubility 10% na mmiri | Kpochapụ ya na agba uhie |
| Uru mkpochapu | Er/Eo: Nken1.1 |
| Ngụkọta ọnụ ọgụgụ microbial cfu/g | Kachasị 100 |
| Akpụkpọ anụ/Yast | Adịghị |
| Mmalite | Obi ịnyịnya |
Akwụkwọ akụkọ na-apụta na-egosi na bisphenol A (BPA), endocrine zuru ebe niile na-akpaghasị kemịkalụ, mgbe mkpughe na-eme na nwata, nwere ike ịbawanye ohere nke ọrịa metabolic.N'ime ọmụmụ ihe a, anyị nyochara echiche ahụ na ikpughe perinatal na BPA na-ebute ụmụ nwere ọrịa imeju abụba: ngosipụta imeju nke ọrịa metabolic, na usoro ya nwere ike ime.A na-enye oke Wistar dị ime na BPA (40μg / kg / ụbọchị) ma ọ bụ ụgbọ n'oge ime na ịmụ nwa.A na-enyocha akụkọ ihe mere eme imeju, nyocha biochemical, transcriptome, na ọrụ mitochondrial na ụmụ nwoke na postnatal 3, 15 na 26 izu.N'ime izu 3 nke afọ, a hụghị ọdịdị imeju na ọrụ na-adịghị mma na ụmụ BPA ekpughere, mana mbelata ọrụ mitochondrial respiratory complex (MRC) (I na III) na mgbanwe dị ukwuu na mkpụrụ ndụ ihe nketa nke metụtara mitochondrial fatty acid metabolism bụ. hụrụ ma e jiri ya tụnyere njikwa.Na izu 15, micro-vesicular steatosis na imeju, mkpụrụ ndụ ihe nketa na-achịkwa nke na-etinye aka na ụzọ lipogenesis, ụbara ọgbọ ROS na ntọhapụ Cytc na ụmụ BPA na-ekpughere.Mgbe ahụ, a na-ahụ nnukwu mkpokọta abụba na imeju na ọbara ALT dị elu na ụmụ ekpughere BPA na izu 26.N'ihe nleba anya ogologo oge, ọrụ mitochondrial imeju gụnyere ọrụ MRC, mmepụta ATP, ọgbọ ROS na ike akpụkpọ anụ mitochondrial ji nwayọọ nwayọọ na-akawanye njọ n'ime ụmụ ekpughere BPA.Perinatal BPA ikpughe na-enye aka na mmepe nke ịba ọcha n'anya steatosis n'ime ụmụ oke, nke enwere ike ịgbazite site na ọrụ mitochondrial imeju na-adịghị mma yana nhazi nke imeju lipid metabolism.
