Ngwaahịa

Ọrịa shuga mellitus na-emetụta ọzịza na-adịghị ala ala na nrụgide oxidative.Bupleurum Polysaccharides (BPs), dịpụrụ adịpụ na Bupleurum smithii var.parvifolium nwere mgbochi mkpali na mgbochi oxidative Njirimara.Otú ọ dị, a maara ntakịrị ihe banyere ọgwụgwọ ọgwụgwọ ya na ọrịa shuga.N'ime nnwale a, a nyochara mmetụta nke BP na ibelata ọrịa shuga na usoro ndị dị n'okpuru.Ewubere ụdị oke oke ọrịa shuga site na intraperitoneal injections nke streptozotocin (100 mg/kg arọ ahụ) ruo ụbọchị abụọ.Ahọpụtara ụmụ oke nwere ọkwa glucose dị elu karịa 16.8mmol/L maka nnwale.Ejiri ọnụ BPs (30 na 60 mg/kg) were ọnụ na-enye ụmụ oke ndị ọrịa shuga otu ugboro n'ụbọchị maka ụbọchị 35.Ọ bụghị naanị na BP na-ebelata ọkwa glucose ọbara nke ukwuu, kamakwa ọ na-abawanye nke insulin serum na glycogen imeju na ụmụ oke ndị nwere ọrịa shuga ma e jiri ya tụnyere ụmụ oke ụdị.Na mgbakwunye, nchịkwa BP mere ka okwu insulin dịkwuo mma ma gbochie apoptosis na pancreas nke ụmụ oke na-arịa ọrịa shuga.Nleba anya na akụkọ ihe mere eme gosikwara na BP na-echebe pancreas na imeju site na mmebi oxidative na mkpali.Nsonaazụ ndị a na-egosi na BP na-echebe mkpụrụ ndụ β pancreatic na hepatocytes imeju na imeju ọrịa shuga, nke jikọtara ya na ihe mgbochi oxidative na mgbochi mkpali.