Iodonitrotetrazolium chloride CAS: 146-68-9
| Nọmba katalọgụ | XD90473 |
| Aha ngwaahịa | Iodonitrotetrazolium chloride |
| CAS | 146-68-9 |
| Usoro ihe omimi | C19H13ClIN5O2 |
| Ibu molekụla | 505.70 |
| Nkọwa nchekwa | 2 ruo 8 Celsius C |
| Koodu tarifu akwadoro | 32129000 |
Nkọwapụta ngwaahịa
| njirimara | H-NMR |
| Ọdịdị | Ìhè odo ka oroma ntụ ntụ |
| Nyocha | > 99% |
| Solubility | Kpochapụ ngwọta |
Interferon na-ebute protein transmembrane 1 (IFITM1) bụ otu n'ime ndị ezinaụlọ protein transmembrane na-ebute interferon.N'ime ọmụmụ ihe a, anyị kọrọ na okwu IFITM1 dị elu na ọrịa cancer colorectal mmadụ (CRC) jikọtara ya na CRC lymph node na anya metastasis yana ọkwa ụlọ ọgwụ dị elu karị.N'ụzọ dị mkpa, okwu IFITM1 dị elu bụ ihe na-eme ka ọ dịrị ndụ na-adịghị mma.Iji nyochaa usoro mkpụrụ ndụ ihe nketa, anyị gosipụtara na nkwupụta nke IFITM1 n'ime sel CRC na-akwalite, ebe nkwụsị nke okwu IFITM1 na-egbochi, mbugharị cell / mbuso agha na tumorigenicity in vitro.Ọzọkwa, anyị chọpụtara Caveolin-1 (CAV1) dị ka mgbada mgbada nke mbuso agha cell nke IFITM1, dị ka knockdown nke CAV1 kpochapụrụ siIFITM1 mgbasa ozi mgbochi nke mbuso agha cell na sel CRC.Na mgbakwunye, na otu CRC nke ndị ọrịa 229, okwu nke IFITM1 jikọtara ya na okwu CAV1.Nsonaazụ ndị a tụrụ aro na IFITM1 na-akwalite ịdị mkpa nke mkpụrụ ndụ CRC, yana ọ bụ ihe nrịbama prognostic na ebumnuche ọgwụgwọ maka CRC.
