Ngwaahịa

Ihe mejupụtara biofilms bụ mkpụrụ ndụ nje na-etinye n'ime matrix polymeric extracellular nke arụpụtara onwe ya.Poly-beta (1,6) -N-acetyl-d-glucosamine (PNAG) bụ isi ihe matrix biofilm na nje bacteria dị iche iche.N'ime ọmụmụ ihe a, anyị nyochara njirimara anụ ahụ na kemịkal nke PNAG matrix na biofilms mepụtara in vitro site na gram-negative porcine respiratory pathogen Actinobacillus pleuropneumoniae na gram-positive ngwaọrụ metụtara Staphylococcus epidermidis.Achọpụtara mmetụta PNAG na nnukwu mmiri na-asọpụta site n'ịtụ ọnụego nke convection mmiri site na biofilms emebere na ngwaọrụ nzacha centrifugal.Ọnụ ọgụgụ nke convection nke mmiri dị elu nke ukwuu na biofilms azụlitere na ọnụnọ nke PNAG na-emebi emebi enzyme dispersin B karịa na biofilms emebere na-enweghị enzyme, na-egosi na PNAG na-ebelata oke mmiri mmiri.PNAG gbochikwara ibufe quaternary ammonium compound cetylpyridinium chloride (CPC) site na biofilms.Ijikọ CPC na ihe nkiri biofilms na-egbochikwa mkpụkọ mmiri ma gbochie ibuga azo dye Allura red.E wepụrụ CPC Bioactive nke ọma site na biofilms site na ọgwụgwọ na 1 M sodium chloride.Ejikọtara ọnụ, nchoputa ndị a na-atụ aro na CPC na-emeghachi omume ozugbo na matrix PNAG ma gbanwee ihe anụ ahụ na kemịkal ya.Nsonaazụ anyị na-egosi na PNAG na-arụ ọrụ dị mkpa n'ịchịkwa ọnọdụ physiological nke biofilms ma nwee ike itinye aka na usoro ndị ọzọ metụtara biofilm dị ka mgbochi biocide.