Ngwaahịa

Mmekọrịta dị n'etiti ọgwụ antidiabetic, Metformin na nwa ehi thymus DNA (CT-DNA) na (50mM Tris-HCl) ihe nchekwa ka amụrụ site na nnabata UV-Visible absorption, fluorescence, CD spectroscopy na viscosity nha.Na ọmụmụ fluorimetric, enthalpy na entropy nke mmeghachi omume n'etiti ọgwụ na CT-DNA gosipụtara na mmeghachi omume ahụ bụ exothermic (ΔH = -35.4522 kJ mol (-1); ΔS = -49.9523 J mol (-1) K (-1). )).Ọmụmụ ihe na-ejikọta ọnụ na-egosi na ọgwụ ahụ nwere ike ịhapụ Hoechst 33258 kpamkpam.Mgbagwoju anya gosipụtara hyperchromism absorption na ụdịdị UV-Vis ya nwere DNA.The gbakọọ adịgide adịgide adịgide, K (b), nwetara site UV-Vis ọmụmụ absorption bụ 8.3 × 10 (4) M (-1).Ọzọkwa, mgbanwe dị na CD spectra na ọnụnọ nke ọgwụ na-egosi nkwụsi ike nke ụdị B nke CT-DNA nke aka nri.N'ikpeazụ, nha viscosity gosiri na ijikọ mgbagwoju anya na CT-DNA nwere ike ịbụ njikọ elu, tumadi n'ihi njikọ nke groove.Copyright © 2012 Elsevier BV Edebere ikike niile.