Ngwaahịa

Iji dokwuo anya usoro mmalite nke mineralization nke dentin, a na-enyocha mmetụta mgbochi nke 1-hydroxyethylydene-1,1-bisphosphonate (HEBP) na mineralization nke dentin.Ejiri HEBP (8 mg P/kg) gbanye oke (100 g) na subcutaneously maka 7 ma ọ bụ 14 d, a na-ahazi incisors maka Ca histochemistry na / ma ọ bụ microscopy eletrọn.Ihe mgbawa ejiri HEBP mesoo gosipụtara ahịrị ubube ọzọ nke dentin nke mineralized na nke na-abụghị nke mineral na njedebe apical.GBHA kpughere mmeghachi omume Ca na-agafeghị oke na matriks sempulpal dentin nke na-abụghị nke mineral ebe microscopy eletrọn gosipụtara nkesa bara ụba nke ezigbo ntupu dị ka igwe nwere oke igwe.Mantle dentin matrix na-abụghị nke mineral adịghị mma maka Ca mana ọ nwere ọtụtụ vesicles matrix (MVs) jupụtara na nkwụnye ego kristal na/ma ọ bụ amorphous.Nrụpụta mineral nke sekọmpulpal dentin mere n'adabereghị na oyi akwa akwa akwa akwa akwa MV n'ụdị emetụtara.Ihe omuma anyi na-enye ihe akaebe histochemical nke ihe nwere ike ime ca-jide nke matriks dentin sempulpal na anọghị ya na dentin mantle ebe MV-mediated mineralization na-eme.Na dentin mantle, HEBP anaghị egbochi uto kristal na MV kama ọ na-egbochi ntolite ya mgbe akpụkpọ ahụ gbawara.A na-atụ aro na sekọmpulpal dentin matrix nwere ikike ịnweta mineral na-adabereghị na MV-mediated mineralization of mantle dentin, ọ bụ ezie na MV na-ekpebi saịtị mbụ na oge nke mineralization dentin.