Doxycycline hyclate CAS: 24390-14-5 99% odo crystalline ntụ ntụ
| Nọmba katalọgụ | XD90368 |
| Aha ngwaahịa | Doxycycline hyclate |
| CAS | 24390-14-5 |
| Usoro ihe omimi | C22H24N2O8·HCl·0.5C2H6O·0.5H2O |
| Ibu molekụla | 512.94 |
| Nkọwa nchekwa | 2 ruo 8 Celsius C |
| Koodu tarifu akwadoro | 29413000 |
Nkọwapụta ngwaahịa
| adịghị ọcha A | <2% |
| adịghị ọchaB | <2% |
| Ntughari pụrụ iche | -105 ruo -120 |
| pH | 2-3 |
| adịghị ọcha C | <0.5% |
| adịghị ọchaD | <0.5% |
| Ọnwụ na ihicha | 1.4-2.8% |
| Nyocha | 99% |
| Ihe fọdụrụ na mgbanye | <0.4% |
| Absorbtivity | 300-335 |
| Otu adịghị ọcha ọ bụla ọzọ | <0.5% |
| Ọdịdị | Odo kristal ntụ ntụ |
| adịghị ọcha F | <0.5% |
| adịghị ọchaE | <0.5% |
| Mmanya ethyl | 4.5-6% |
| Absorbency nke adịghị ọcha | <0.07% |
Nhazi biofilm na mmebi eze nwere ike ibute mucositis peri-implant na peri-implantitis na-esote.A na-eji ọgwụ nje mee ihe dị ka doxycycline (Doxy).N'ebe a, anyị jiri usoro electrochemical nke cathodic polarization kpuchie Doxy n'elu elu nke ihe eji eme eze.Elu nke mkpuchi Doxy gosipụtara ntọhapụ gbawara n'ime saline buffered phosphate n'ime awa 24 mbụ.Otú ọ dị, ọnụ ọgụgụ dị ịrịba ama nke Doxy nọgidere na-adị n'elu ma ọ dịkarịa ala izu 2 karịsịa na nlele 5 mA-3 h nke nwere oke Doxy dị elu, na-atụ aro ma mmalite na ogologo oge bacteriostatic ikike nke elu mkpuchi.A tụlere kemịkalụ dị n'elu site na x-ray photoelectron spectroscopy na ion mass spectrometry nke abụọ.A tụlere ọdịdị elu elu site na nyocha eletrọn microscopy na profilometry na-acha anụnụ anụnụ.Ogologo oge polarization site na 1 h ruo 5 h na njupụta dị ugbu a dị elu site na 1 ruo 15 mA cm(-2) butere nnukwu Doxy na surfa ce.Ekpuchiri elu ahụ site na akwa Doxy na-erughị 100 nm na-enweghị mgbanwe dị ukwuu na ọdịdị elu elu.A na-enyocha ihe onwunwe antibacterial nke elu Doxy mkpuchi site na biofilm na nyocha uto planktonic site na iji Staphylococcus epidermidis.Ihe nlele doxy nwere mkpuchi belatara ma mkpokọta biofilm na uto planktonic na omenala broth, ma gbochiekwa uto nje na efere agar.Mmetụta nje bacteria siri ike maka ihe atụ nke 5 mA-3 h nke ejiri nnukwu Doxy kpuchie ya ma e jiri ya tụnyere nke 1 mA-1 h.N'ihi nke a, elu abutment nke ejiri Doxy kpuchie nwere ikike igbochi ịchịisi nje bacteria mgbe ekpughere ya na oghere ọnụ.Ihe mkpuchi doxy nwere ike ịbụ ụzọ dị mma iji chịkwaa mucositis peri-implant ma gbochie ọganihu ya na peri-implantitis.
