BETA-NADPH TETRA(CYCLOHEXYLAMMONIUM) Nnu Cas: 100929-71-3
| Nọmba katalọgụ | XD90431 |
| Aha ngwaahịa | BETA-NADPH TETRA (CYCLOHEXYLAMMONIUM) nnu |
| CAS | 100929-71-3 |
| Usoro ihe omimi | C21H30N7O17P3.4[C6H13N] |
| Ibu molekụla | 1142.11748 |
| Nkọwa nchekwa | -20 Celsius |
Nkọwapụta ngwaahịa
| Ọdịdị | Ọcha ntụ ntụ |
| Nyocha | 99% |
NADPH oxidases bụ ezinụlọ nke enzymes na-emepụta ụdị oxygen na-emeghachi omume (ROS).NOX1 (NADPH oxidase 1) na NOX2 oxidases bụ isi mmalite nke ROS na mgbidi akwara na ọnọdụ ndị dị ka ọbara mgbali elu, hypercholesterolemia, ọrịa shuga na ịka nká, ya mere, ha bụ ihe dị mkpa na-enye aka na nrụgide oxidative, nkwụsị nke endothelial na ọrịa vaskụla nke na-akpata. nhazigharị akwara na atherogenesis.Na nyocha a, anyị na-akwalite echiche ahụ ma e jiri ya tụnyere iji ọgwụ antioxidants eme ihe, na-egbochi NOX1 na NOX2 oxidases bụ ụzọ dị mma maka ịlụso nrụgide oxidative ọgụ.Anyị na-akọwa nkenke nkenke ụfọdụ ihe mgbochi NADPH oxidase putative na apụta.Na mgbakwunye, anyị na-egosipụta ọrụ dị oke mkpa nke NADPH oxidase regulatory subunit, p47phox, na ọrụ nke vaskụla NOX1 na NOX2 oxidases, ma na-atụ aro ka nghọta ka mma nke mmekọrịta molekụla ya kpọmkwem nwere ike isi mee ka mmepe nke isoform-ahọrọ ọgwụ ọhụrụ iji gbochie. ma ọ bụ na-agwọ ọrịa scular cardiova.
