2,3,5-Triphenyl-2H-tetrazolium chloride Cas: 298-96-4 98% Gbanyụọ-acha ọcha / icha mmirimmiri odo crystalline ntụ ntụ.
Nọmba katalọgụ | XD90154 |
Aha ngwaahịa | 2,3,5-Triphenyl-2H-tetrazolium chloride |
CAS | 298-96-4 |
Usoro ihe omimi | C19H15N4·Cl |
Ibu molekụla | 334.80 |
Nkọwa nchekwa | 2 ruo 8 Celsius C |
Koodu tarifu akwadoro | 29339980 |
Nkọwapụta ngwaahịa
Ọdịdị | Gbanyụọ-ọcha/ọcha odo odo crystalline ntụ ntụ |
Asay | Min.98% |
Ebe mgbaze | 235-245 Deg C |
Ọnwụ na ihicha | <3.0% |
Ọdịnaya Mmiri | 0.5% kacha |
Ihe fọdụrụ na mgbanye | Oke.0.5% |
Solubility na EtoH | Gafe |
Solubility na ethanol | Kpochapụ ma zuo oke |
Iji nyochaa uru bara uru nke ngwakọta nke butyrate, Lactobacillus casei, na L-carnitine na ụdị oke colitis. E kewara oke n'ime otu asaa.Otu anọ natara butyrate ọnụ, L-carnitine, Lactobacillus casei na ngwakọta nke ndị nnọchite atọ maka ụbọchị iri n'usoro.Ndị otu ndị fọdụrụ gụnyere njikwa na-adịghị mma na nke dị mma na otu cham.Macroscopic, histopathological tests, na biomarkers dị ka tumor necrosis factor-alpha (TNF-α) na interlukin-1β (IL-1β), myeloperoxidase (MPO), thiobarbituric acid reactive bekee (TBARS), na ferric belatara ikike nke plasma (FRAP). ) e kpebisiri ike na colon. Usoro ọgwụgwọ ahụ gosipụtara mmetụta bara uru dị ukwuu na ibelata colitis ma e jiri ya tụnyere njikwa.Mgbanwe zuru oke na Mbelata TNF-α (114.66 ± 18.26 vs 171.78 ± 9.48 pg / mg protein, P <0.05), IL-1β (24.9 ± 1.07 vs 33.06 ± 2.16 pg/mg protein, P), <2.0.05. ± 0.03 vs 0.49 ± 0.04 μg/mg protein, P <0.01), MPO (15.32 ± 0.4 vs 27.24 ± 3.84 U/mg protein, P <0.05), na elu nke FRAP (23.46 ± 5.2 ± 1.2 μl / mo. , P <0.05) na-akwado mmasị nke usoro ọgwụgwọ ngwakọta ma e jiri ya tụnyere njikwa.Ọ bụ ezie na monotherapies nwekwara ike imeziwanye ihe nrịbama nke colitis, ọgwụgwọ nchikota ahụ ka mma iji meziwanye ihe nrịbama mgbakasị ahụ nke colon oxidative gụnyere FRAP, TBARS, na MPO. Ngwakọta dị ugbu a bụ ngwakọta kwesịrị ekwesị na njikwa nke colitis nnwale na a ga-anwale ya. ntọala ụlọ ọgwụ.