1,1-Cyclobutanedicarboxylatodiammineplatinum (II) Cas: 41575-94-4
| Nọmba katalọgụ | XD90684 |
| Aha ngwaahịa | 1,1-Cyclobutanedicarboxylatodiammineplatinum (II) |
| CAS | 41575-94-4 |
| Usoro ihe omimi | C6H12N2O4Pt |
| Ibu molekụla | 371.25 |
| Nkọwa nchekwa | 2-8 Celsius C |
| Koodu tarifu akwadoro | 28439090 |
Nkọwapụta ngwaahịa
| Ọdịdị | Na-acha ọcha na-acha ọcha ntụ ntụ |
| Nyocha | 99% |
| Mmiri | ≤0.5% |
| Ọnwụ na ihicha | ≤0.5% |
| Chlorides | ≤100ppm |
| Ihe ndị emetụtara | ≤0.25% |
| Ọdịghị ọcha ọ bụla akọwapụtaghị | ≤0.1% |
| Ihe adịghị ọcha ndị ọzọ niile | ≤0.5% |
| 1,1-Cyclobutanedicarboxylic acid | 0.5% |
Ọgbọ nke abụọ platinum mgbagwoju antineoplastic ọgwụ.Arụ ọrụ antitumor na antitumor yiri nke cisplatin, ma mmiri solubility dị mma karịa nke cisplatin, na nsị na akụrụ dịkwa ala.Ọ na-enwe mmetụta dị mma na-agwọ ọrịa na obere cell akpa ume cancer, ovarian cancer, isi na olu squamous cell carcinoma, testicular tumor, malignant lymphoma, etc. Ọ nwekwara ike iji maka cervical cancer, eriri afo cancer, wdg.
Ọgwụ anticancer platinum nke ọgbọ nke abụọ nwere otu ọrụ na ojiji dị ka cisplatin.Ọ na-arụsi ọrụ ike karịa cisplatin maka ụfọdụ etuto ahụ, ma sie ike karịa cisplatin dị ka rediosensitizer n'okpuru ọnọdụ hypoxic.A na-eji ya eme ihe maka ọrịa cancer akpa nwa, ọrịa cancer testicular, ọrịa cancer akpa ume obere cell na kansa isi na olu.
Carboplatin bụ ọgwụ mgbochi ọrịa cancer nke dabeere na platinum nke na-emebi DNA site n'ịme njikọ intrachain na ihe fọdụrụ guanine dị n'akụkụ.A na-enweta mmetụta antitumor nke ọgwụ ndị a site n'ịkwụsị ọrụ mmezigharị DNA mismatch (MMR) yana iwebata ọnwụ sel emebere.
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