Thiamphenicol Cas: 15318-45-3
Nọmba katalọgụ | XD92378 |
Aha ngwaahịa | Thiamphenicol |
CAS | 15318-45-3 |
Ụdị molekụlala | C12H15Cl2NO5S |
Ibu molekụla | 356.22 |
Nkọwa nchekwa | Ambient |
Koodu tarifu akwadoro | 29414000 |
Nkọwapụta ngwaahịa
Ọdịdị | White crystalline ntụ ntụ |
Asay | 99% nkeji |
Ebe mgbaze | 163°C -167°C |
Ọla dị arọ | ≤10ppm |
Ọnwụ na ihicha | ≤1.0% |
Ntụgharị anya pụrụ iche | -21°-24° |
Chloride | ≤0.02% |
Thiamphenicol bụ ọgwụ nje chloramphenicol sara mbara, nke dị irè karịa nje bacteria gram-adịghị mma karịa nje bacteria gram-positive.N'ime ụlọ okpomọkụ, ọ bụ ihe na-acha ọcha na-acha ọcha crystalline ntụ ntụ ma ọ bụ crystal, nke nwere ike ngwa ngwa na kpamkpam absorption site n'ọnụ adminstration, nakwa dị ka ọ na excreted tumadi na prototype si mmamịrị maka metabolism.A na-etinye ya n'ụlọ ọgwụ maka ọgwụgwọ iku ume, urinary tract, imeju na gallbladder, typhoid na ịwa ahụ eriri afọ ndị ọzọ, gynecology na ọrịa ENT.Karịsịa na ọrịa ndị dị nro ọ na-adị irè karị.Ọ nwere usoro kemịkal yiri ya na chloramphenicol.methyl sulfone ya nọchiri anya nitro nke chloramphenicol, bụ nke belatara nsị ya, na na vivo ọrụ nje nje ya dị ike ugboro 2.5-5 karịa chloramphenicol.Maka nje bacteria gram-positive, dị ka streptococcus pneumoniae na hemolytic streptococcus, ọ nwere mmetụta antibacterial siri ike, ebe maka nje bacteria gram-adịghị mma, dị ka Neisseria gonorrhoeae, meningococcus, lung Bacteroides, E. coli, Vibrio cholerae, Shigella influenza na bacillus. ọ nwekwara mmetụta antibacterial siri ike.Maka nje bacteria anaerobic, Rickettsia na amoeba, ọ nwere mmetụta antibacterial n'ókè ụfọdụ.O nwere otu usoro antimicrobial na chloramphenicol, nke na-egbochi njikọ nke protein nje.A na-etinye ọgwụ a ngwa ngwa site na nchịkwa ọnụ, nke na-erute ọnụ ọgụgụ ọbara kacha elu n'ime awa abụọ.Ọkara ndụ ya bụ awa 5, nke dị ogologo karịa chloramphenicol.Nje bacteria nwere nguzogide ya zuru oke na chloramphenicol, ebe nje bacteria nwere ụfọdụ ihe na-eguzogide ya na tetracycline.
Thiamphenicol nwekwara mmetụta immunosuppressive siri ike, nke bụ ezigbo immunosuppressant.Usoro ya na-eme ihe dị nnọọ iche na ndị ọzọ immunosuppressive agents.Mmetụta immunosuppressive dị ọtụtụ ugboro karịa chloramphenicol.Ọ nwere ike ịbụ dị ka ihe ndọtị dị irè maka mmeghachi omume ntụgharị na ịwa ahụ allogeneic transplantation.