Tetracycline hydrochloride CAS: 64-75-5 99% odo crystalline ntụ ntụ
| Nọmba katalọgụ | XD90366 |
| Aha ngwaahịa | Tetracycline hydrochloride |
| CAS | 64-75-5 |
| Usoro ihe omimi | C22H24N2O8 · HCl |
| Ibu molekụla | 480.90 |
| Nkọwa nchekwa | -15 ruo -20 Celsius |
| Koodu tarifu akwadoro | 29413000 |
Nkọwapụta ngwaahịa
| Mmechi | Na-akwado BP2013, EP7, USP38 |
| Ọla dị arọ | <0.005% |
| Otu adịghị ọcha | <0.1% |
| njirimara | IR, UV, HPLC, TLC |
| pH | 1.8-2.8 |
| Ọnwụ na ihicha | <2.0% |
| Ihe mgbaze fọdụrụnụ | n-Butanol <3000ppm |
| Nyocha | BP2013/EP7 99% |
| Sulfated Ash | <0.5% |
| Ntụgharị anya pụrụ iche | -240 ruo -255° |
| Ike | USP 38:>900ug/mg |
| Mgbakọta adịghị ọcha | <5% |
| Ọdịdị | Odo kristal ntụ ntụ |
| 4-epianhydrotetracycline | <2% |
| Oke microbial | Na-akwado |
| 4-Epiteracycline | <3% |
| Anhydrotetracyline | <0.5% |
| Chlortetracycline Hydrochloride | <0.5% |
| Ihe mgbaze fọdụrụnụ | <100ppm |
Ekenyela mmepe nke nguzogide antimicrobial maka oke na iji ọgwụ nje eme ihe n'ụzọ na-ezighị ezi.Staphylococci bụ akụkụ nke ahịhịa nkịtị mana ọ bụkwa ihe na-akpata ọrịa nwere ike bụrụ nke na-eguzogide ọtụtụ ọgwụ nje a ma ama.Mgbochi na coagulase negative staphylococci (ConS) na-atụ aro ịmalite n'ihi nrụgide nhọrọ dị mma na-eso ọgwụgwọ ọgwụ nje.Ọmụmụ ihe a nyochara ọnụnọ nke ọgwụ nje nje nje itoolu a na-ejikarị na mmamịrị mmadụ sitere na ndị ọrịa na-apụ n'ụlọ ọgwụ abụọ dị na Ghana n'ihe metụtara nguzogide CoNS.A na-enyocha mmamịrị na CoNS (n = 246 na n = 96 n'otu n'otu) site na ndị ọrịa n'ụlọọgwụ abụọ na Ghana.Achọpụtara CONS site na iji Gram staining, coagulase test, na MALDI-TOF/MS, na ihe mgbochi nje na 12 a na-ejikarị eme ihe na-ekpebi site na mgbasa diski.Ọzọkwa, e mepụtara usoro nyocha maka mkpebi nke itoolu a na-ejikarị eme ihe antimicrobial na Ghana site na iji mmịpụta siri ike-ph ase yana HPLC-MS/MS na-eji ionization spray electron.A hụrụ ugboro kachasị elu nke iguzogide CoNS maka penicillin V (98%), trimethoprim (67%) na tetracycline (63%).S. hemolyticus bụ nke a na-ahụkarị (75%), S. epidermidis (13%) na S. hominis (6%) sochiri ya.S. hemolyticus bụkwa ụdị na-egosipụta oke nguzogide kachasị (82%).69% nke CoNS dịpụrụ adịpụ bụ ọtụtụ ọgwụ na-eguzogide ọgwụ (≧ 4 ọgwụ nje) yana 45% nke CoNS bụ ndị na-eguzogide ọgwụ methicillin.Achọpụtara ọgwụ nje na 64% nke nlele mmamịrị nyochara (n = 121) ebe ọgwụ nje a na-ahụkarị bụ ciprofloxacin (30%), trimethoprim (27%) na metronidazole (17%).Isi ihe nchoputa nke ihe omumu a bu na onu ogugu nke achoputara na mmamịrị na-adighi nma karia ojiji nke ndi oria na-akuko na onu ogugu nke S. hemolyticus na-eguzogide otutu oge karia umu ConS ndi ozo na-adighi ike mgbe achoputara ihe ndi ozo na mmamịrị.
