Terbinafine hydrochloride Cas: 78628-80-5
Nọmba katalọgụ | XD92374 |
Aha ngwaahịa | Terbinafine hydrochloride |
CAS | 78628-80-5 |
Ụdị molekụlala | C21H25N · HCl |
Ibu molekụla | 327.89 |
Nkọwa nchekwa | -15 ruo -20 Celsius |
Koodu tarifu akwadoro | 29214900 |
Nkọwapụta ngwaahịa
Ọdịdị | Ọcha ntụ ntụ |
Asay | 99% nkeji |
Ebe mgbaze | 204-208 Celsius C |
nchekwa okpomọkụ. | 15-25 Celsius C |
solubility | methanol: soluble 50mg/mL |
erbinafine hydrochloride bụ ụdị ndị ọkachamara n'ihe gbasara anụ ahụ na-eme ihe n'ụdị allyl amine antifungal ọgwụ.Ọ bụ Switzerland Novartis mepụtara ya na 1980, wee pụta n'ahịa UK maka oge mbụ na 1991. FDA nke United States kwadoro maka ọgwụ OTC na 1996, wee pụta n'ahịa nke United States n'otu oge ahụ. afọ.Ka ọ dị ugbu a, a na-ere ọgwụ ahụ n'ihe karịrị mba 90 nke okwu ahụ.Ọ nwere ike ịkọwapụta nsogbu n'oge ikpeazụ nke ndụ ire ere nke sterol ero, na-ahọrọ igbochi ọrụ nke fungal squalene mgbanaka oxidase, ma gbochie squalene epoxidation na nguzobe nke ungal cell akpụkpọ ahụ, si otú igbu ma ọ bụ gbochie n'ọrụ nke ero.Kwesịrị ekwesị maka ọgwụgwọ akpụkpọ anụ candidiasis, dị ka tinea manuum, tinea, tinea, ringworm nke ahụ, tinea versicolor, ọ bụkwa ọgwụ kachasị mma maka ọgwụgwọ onychomycosis.
Terbinafine hydrochloride batara n'ime batch mbụ nke obodo mara ọkwa ndekọ aha OTC na 2000. Ngwaahịa a bụ nke ọgwụ antifungal.Ọ nwere mmetụta siri ike na ọrịa fungal na-emighị emi, ma nwee ike ịgwọ ọtụtụ ọrịa anụ ahụ fungal site na iji mpụga.