Tazobactam Cas: 89786-04-9
| Nọmba katalọgụ | XD92373 |
| Aha ngwaahịa | Tazobactam |
| CAS | 89786-04-9 |
| Ụdị molekụlala | C10H12N4O5S |
| Ibu molekụla | 300.29 |
| Nkọwa nchekwa | -15 ruo -20 Celsius |
| Koodu tarifu akwadoro | 29419000 |
Nkọwapụta ngwaahịa
| Ọdịdị | Na-acha ọcha na-acha ọcha ntụ ntụ |
| Asay | 99% nkeji |
| Mmiri | <0.5% |
| Ntughari pụrụ iche | +127 ruo +139 |
| Ọla dị arọ | <20ppm |
| Ihe fọdụrụ na mgbanye | <0.1% |
| Mgbakọta adịghị ọcha | <1.0% |
Tazobactam bụ penicillanic acid sulfone nke yiri ntụziaka nke sulfactam.Ọ bụ β-lactamaseinhibitor dị ike karịa sulbactam ma nwee ọrụ dị iche iche sara mbara karịa clavulanic acid.Ọ nwere mmetụta antibacterial adịghị ike.Tazobactam dị na ofu-dose, injectable combinations na piperacillin, a sara mbara ụdịdị penicillinconsisting nke 8: 1 ratio nke piperacillin sodium ka tazobactamsodium site arọ na ahịa n'okpuru ahia aha Zosyn. The pharmacokinetics nke ọgwụ abụọ ahụ yiri nnọọ.Ha abụọ nwere obere ndụ ọkara (t1/2 ℃ 1 hour), nwere obere protein, na-enweta obere metabolism ma na-apụ n'ụdị adịghị arụ ọrụ na mmamịrị na nnukwu mkpokọta.
Ngosipụta akwadoro maka piperacillin-tazobactamcombination gụnyere ọgwụgwọ appendicitis, postpartumendometritis, na ọrịa mkpali pelvic kpatara nke beta-lactamase na-emepụta E. coli na Bacteroides spp., ọrịa nhazi akpụkpọ anụ nke β-lactamase-producingS kpatara.aureus, na oyi baa sitere na β-lactamase-na-emepụta ụdị nke H. influenzae.
