Ngwaahịa

Iji nyochaa ọrịa na-efe efe nke mkpụrụ ndụ ihe nketa nke Neisseria gonorrhoeae si Saskatchewan, Canada, na-eji Neisseria gonorrhoeae multi antigen sequence typing (NG-MAST), na iji nyochaa mkpakọrịta n'etiti antimicrobial susceptibility (AMS) na kpọmkwem ụdị strain (STs) .320. , nke anakọtara n'etiti 2003 na 2008, bụ ndị NG-MAST dere.A na-achịkọta ST ma ọ bụrụ na otu n'ime alleles ha na-ahụkarị ma nke ọzọ dị iche site na ≤1% n'usoro DNA.Ekpebiri AMS site na agar dilution (CLSI) ka ọ bụrụ ọgwụ nje asaa.N gonorrheae kewapụrụ iche ka ebibiri n'ime mmadụ 82 n'otu n'otu NG-MAST ST na 18 NG-MAST ST nwere otu 25, 3655, 921, 3654, 3657 na 3656 mejupụtara% 513. /320) nke ndị dịpụrụ adịpụ.N gonorrheae dịpụrụ adịpụ nke nwere ike ịnweta ọgwụ mgbochi nje niile a nwalere bụ nke ukwuu (p<0.05) jikọtara ya na ST 25 (87%).Mkpakọrịta ndị ọzọ dị ịrịba ama n'etiti ST na AMS gụnyere: ST 3654 na iche iche na obere ihe mgbochi mgbochi nke ≥0.03 mg / L ruo ọgbọ nke atọ ceph alosporins;ST 3711 (100%) na TRNG;na ST/otu 3654 (43%) na chromosomal iguzogide penicillin na tetracycline.Ọtụtụ NG-MAST STs/otu dị iche iche jikọtara ya na mwepu nwere chromosomal na-eguzogide tetracycline.Ndị dịpụrụ adịpụ na-eguzogide ciprofloxacin (n=5) na azithromycin (n=2) pụtara dị ka ST n'otu n'otu.Achọpụtara mkpakọrịta dị ịrịba ama n'etiti ndị ST n'otu n'otu, mmekọahụ na afọ nke onye ọrịa, na nkesa mpaghara na nke oge. Achọpụtara njikọ dị n'etiti N gonorrheae AMS na NG-MAST ST ma nwee ike ịba uru n'ịkọ AMS mpaghara.N'ihi na ST na mba dị iche iche na-adịgasị iche iche, iji NG-MAST maka amụma AMS zuru ụwa ọnụ chọrọ ọmụmụ ihe ọzọ.