Ngwaahịa

(S) - (-) N, N-Dimethyl-3-hydroxy-3- (2-thienyl) propanamine bụ ngwakọta chiral nke nwere ngwa dị iche iche n'ọhịa nke ọgwụ. Otu ngwa dị mkpa nke (S) - (-) -N, N-Dimethyl-3-hydroxy-3- (2-thienyl) propanamine dị na mmepe nke ndị na-emechi ihe nchịkwa serotonin (SSRIs).SSRI bụ otu ọgwụ ndị a na-ejikarị agwọ ịda mbà n'obi, nsogbu nchekasị, na ọnọdụ ahụike uche ndị ọzọ.Ngwakọta a na-arụ ọrụ dị ka ihe mmalite ma ọ bụ mmalite ihe na njikọ nke ndị na-emechi ihe nchịkwa serotonin na-ahọrọ, na-enye ohere maka ịmepụta ndị na-emepụta ihe na-emepụta ihe na-eme ka ọ dịkwuo mma.Site n'itinye (S) - (-) N, N-Dimethyl-3-hydroxy-3- (2-thienyl) propanamine n'ime nhazi nke ọgwụ ahụ, ndị nchọpụta nwere ike ịhazi ihe ndị na-emepụta ọgwụ, dị ka njikọ ya maka ndị na-ebu serotonin, na-eme ka arụmọrụ dịkwuo mma ma belata mmetụta ndị ọzọ. Ọzọkwa, (S) - (-) N, N-Dimethyl-3-hydroxy-3- (2-thienyl) propanamine nwere ike iji dị ka ihe mgbochi ụlọ na njikọ nke bioactive ndị ọzọ. ngwakọta.Ọdịdị nke chiral ya na usoro dịgasị iche iche na-eme ka ọ bụrụ ihe mmalite bara uru maka iwu nke ụmụ irighiri ihe dị mgbagwoju anya.Ndị na-eme nchọpụta nwere ike ịrụ ọrụ dị iche iche na saịtị dị na molecule iji webata otu dị iche iche ma ọ bụ gbanwee stereochemistry ya iji mepụta ndị na-achọ ọgwụ ọjọọ. Ọzọkwa, (S) - (-) N, N-Dimethyl-3-hydroxy-3- (2-thienyl) propanamine. a mụọla maka iji ya na-agwọ ọrịa Parkinson.Nnyocha egosila na ogige a na-egosipụta ọrụ agonist dopamine, nke pụtara na ọ nwere ike ịkpali ndị na-anabata dopamine, nke na-emetụtakarị na ọrịa Parkinson.Ọ nwere ike ịnwe ike ọgwụgwọ na ibelata mgbaàmà ndị metụtara ọrịa neurodegenerative a. Ọ dị mkpa iburu n'obi na (S) - (-) N, N-Dimethyl-3-hydroxy-3- (2-thienyl) propanamine bụ ihe dị ike. ngwakọta, na ojiji ya kwesịrị iji nlezianya mee ya.Ndị na-eme nchọpụta na ndị ọkachamara na-arụ ọrụ na ogige a kwesịrị ịgbaso ụkpụrụ na usoro nchekwa iji hụ na njikwa kwesịrị ekwesị ma belata ihe ize ndụ.Na nchịkọta, (S) - (-) N, N-Dimethyl-3-hydroxy-3- (2-thienyl). )propanamine bụ ihe bara uru na mmepe nke ndị na-emechi ihe nchịkwa serotonin na-ahọrọ na ụmụ irighiri ihe ndị ọzọ.Ọdịdị chiral ya, nhazi dị iche iche, na ihe omume ọgwụgwọ nwere ike ime ka ọ bụrụ ihe mgbochi ụlọ dị mkpa na nyocha ọgwụ.Ọmụmụ ihe na-aga n'ihu na nyocha nke (S) - (-) N, N-Dimethyl-3-hydroxy-3- (2-thienyl) propanamine nwere ike inye aka na mmepe nke ọgwụ ọhụrụ na ọgwụgwọ ndị nwere ike ịgwọ ọrịa dị iche iche.