Penicillin G potassium nnu CAS: 113-98-4 99% ntụ ntụ ọcha
| Nọmba katalọgụ | XD90351 |
| Aha ngwaahịa | Penicillin G potassium nnu |
| CAS | 113-98-4 |
| Usoro ihe omimi | C16H17KN2O4S |
| Ibu molekụla | 372.48 |
| Nkọwa nchekwa | Ambient |
| Koodu tarifu akwadoro | 29411000 |
Nkọwapụta ngwaahịa
| Ọnwụ na ihicha | <1.0% |
| Agba nke Ngwọta | Ọ bụghị nnukwu agba karịa ike Y2 ma ọ bụ YG2 nke oke ntụaka |
| pH | 5-7.5 |
| Ihe ndị emetụtara | <1.0% |
| Nyocha | 99% |
| Ike | 1440-1680u/mg |
| Ọdịdị | Ọcha ka ọ fọrọ nke nta ka ọ bụrụ ntụ ntụ crystalline ọcha |
| Ngwọta doo anya | Ọ bụghị karịa opalescent karịa nkwusioru ntụaka 1 |
| nnyefe | NLT 90% |
| Butyl acetate | NMT 0.05% |
| Butanol | NMT 0.12% |
e kọwara na mbụ na molekul autoinducer, nke a kọwara dị ka 1,3-diaminopropane (1,3-DAP), bụ Penicillium chrysogenum na Acremonium chrysogenum zoro ezo.N'iji omenala fermentor na-achịkwa pH anyị ahụla n'ọrụ a na 1,3-DAP na spermidine na-akpali biosynthesis nke benzylpenicillin na P. chrysogenum, ma na nkọwapụta yana na mgbasa ozi mmepụta penicillin siri ike.Ma 1,3-DAP na spermidine, ma ọ bụghị putrescine (1,4-diaminobutane), na-emepụta mmụba dị egwu na ọkwa transcript nke penicillin biosynthetic genes pcbAB, pcbC na penDE.Ndị polyamines ndị a anaghị emetụta nkwupụta nke pH-stress regulator pacC gene, si otú a na-ewepu na mmetụta nke 1,3-DAP na spermidine bụ n'ihi mgbanwe nke usoro nchịkwa pH.Ngosipụta nke mkpụrụ ndụ ihe nketa nke penicillin atọ na-ebelata nke ukwuu na mutant nke P. chrysogenum, nke na-emepụta ọkwa benzylpenicillin dị ala.N'ụzọ na-akpali mmasị, 1,3-DAP na spermidine na-eweghachite mmetụta nke mmụgharị ịkụ aka laeA, na-eweghachite ọkwa nke mmepụta penicillin kpamkpam.Ọzọkwa, 1,3-DAP na spermidine kwalitere okwu nke laeA na nsogbu ndị nne na nna wee weghachi ọkwa nke ederede laeA na mutant laeA ịkụda ala.Ejikọtara nsonaazụ ndị a na-egosi na mmetụta mkpali nke ụmụ irighiri ihe inducer 1,3-DAP na spermidine na-arụ ọrụ, ma ọ dịkarịa ala n'otu akụkụ, site na mkpali nke okwu laeA, onye na-achịkwa ụwa nke na-eme epigenetically na ngosipụta nke mkpụrụ ndụ metabolite nke abụọ. site na nhazigharị heterochromatin.
