Nystatin dihydrate CAS: 1400-61-9 Nystatin A1> 85%;ogige ọ bụla ọzọ
Nọmba katalọgụ | XD90352 |
Aha ngwaahịa | Nystatin dihydrate |
CAS | 1400-61-9 |
Usoro ihe omimi | C47H75NO17 · 2H2O |
Ibu molekụla | 962.10 |
Nkọwa nchekwa | -15 ruo -20 Celsius |
Koodu tarifu akwadoro | 29419000 |
Nkọwapụta ngwaahịa
Mmechi | Dabara na Ph.Eur.9.7 |
Pseudomonas aeruginosa | Adịghị |
pH | 6.0-8.0 (3% ngwọta mmiri) |
Nyocha | Nystatin A1> 85%;ogige ọ bụla ọzọ <4% |
Ọnwụ na ihicha | <5.0% |
Ọdịdị | Uzuzu odo odo ma ọ bụ aja aja |
Sulfated ntụ | <3.5% |
Nnwale ID D | Nkwekọrịta (UV) |
TAMC | <1000cfu/g |
TYMC | <100cfu/g |
Staphylococcus Aureus | Adịghị |
Mgbochi mgbaze methanol | <3000ppm |
Mesityloxide | <500ppm |
Ihe mgbaze fọdụrụnụ | <5000ppm |
Nnwale njirimara (UV) A | yiri ya na ntụaka |
Mwepu A305 | > 0.6 |
nje bacteria gram-adịghị mma (E.coli + Salmonella sp.) | Adịghị |
Clostridia ụdị | Adịghị |
Ihe mgbaze ndị fọdụrụ (1-butanol) | <1000ppm |
Ịdị ọcha; Microbial Assay | NLT> 4400 IU / mg na ndabere a mịrị amị |
Iji chọpụta mgbanwe ụlọ ọgwụ iji chọpụta ọdịiche dị na aspergillosis pulmonary invasive (IPA) site na ịchịisi na ndị ọrịa nwere pneumopathies na-adịghị ala ala nwere ọdịbendị dị mma nke Aspergillus spp.n'ihe nlele iku ume.Ọmụmụ otu ndị na-atụgharị azụ gụnyere ndị ọrịa nwere oke iku ume nke Aspergillus spp.n'ime oge nke afọ 10.A tụlere IPA dịka njirisi Bulpa siri dị.A chịkọtara mgbanwe ụlọ ọgwụ wee mee nyocha nyocha nke mgbagha ọtụtụ ihe. Ndị ọrịa iri asatọ na atọ nwere ikewapụ Aspergillus spp.sitere na nlele iku ume gụnyere;68.7% (n=57) nke ndị ọrịa nwere ọrịa na-adịghị ala ala obstructive pulmonary, 18% (n=15) pulmonary fibrosis na 13.3% (n=11) bronchial asthma.Ndị ọrịa iri abụọ na abụọ (26.6%) nwere IPA.Ojiji nke fluconazole (OR 4.49; CI 95% 1.5-13.4; P = .007), nnukwu iku ume iku ume (OR 4.64; CI 95% 1.46-14.72; P = .009) na oge ụlọ ọgwụ (OR 1.05; CI 95% 1.01-1.1; P = .006) jikọtara ya na IPA. Tupu ojiji nke fluconazole, nnukwu iku ume iku ume na oge ụlọ ọgwụ na-ejikọta ya na IPA na ndị ọrịa nwere pneumopathies na-adịghị ala ala na akụkụ iku ume nke Aspergillus spp.Copyright © 2012 Elsevier España, SL Ikike niile. edobere