Ngwaahịa

N (ε) -trifluoroacetyl-L-lysine bụ ihe nrụpụta kpọmkwem nke amino acid lysine, ebe epsilon (ε) amino group na-echebe site na otu trifluoroacetyl (TFA).Ngwa a na-achọta ngwa n'ebe dị iche iche, karịsịa na peptide synthesis na biochemical research.One isi ojiji nke N (ε) -trifluoroacetyl-L-lysine bụ na siri ike-phase peptide synthesis (SPPS).Peptides na-ekere òkè dị mkpa n'ọtụtụ usoro ndu, na njikọ ha na-achọ mgbakọ amino acid n'usoro.Ndị otu nchekwa TFA na epsilon amino group nke lysine na-egbochi mmeghachi omume ndị a na-achọghị n'oge nhazi njikọ peptide ma na-ahapụ amino asịd ndị ọzọ ka ha nwee ike ịlụ di na nwunye n'ọnọdụ achọrọ.Ozugbo mgbakọ peptide zuru ezu, enwere ike iwepụ otu nchebe TFA nke ọma, yana N (ε) -trifluoroacetyl-L-lysine residue nwere ike gbasaa ọzọ iji mee ka usoro peptide dị iche iche.N (ε) -trifluoroacetyl-L-lysine bụkwa nke ọzọ. ejiri ya na nyocha biochemical iji mụọ usoro protein, ọrụ, na mmekọrịta.Ọ nwere ike ịbụ ngwá ọrụ iji nyochaa ọrụ nke lysine residues na mmekọrịta protein-protein, mmekọrịta protein-DNA, na mgbanwe mgbanwe ntụgharị.Site n'iwebata ìgwè TFA, ihe ndị na-emepụta ọgwụ nke lysine nwere ike gbanwee, na-enye ohere maka nyocha nke usoro mgbasa ozi lysine kpọmkwem na usoro ndu. Ọzọkwa, N (ε) -trifluoroacetyl-L-lysine nwekwara ike ịchọta ngwa na mmepe nke ezubere iche. usoro nnyefe ọgwụ.Site na ijikọta ndị na-ahụ maka ọgwụgwọ kpọmkwem na lysine residue site na otu TFA, ọ ga-ekwe omume ịbawanye nkwụsi ike na nhọrọ nke ọgwụ ahụ, na-eduga n'ịdị mma na-ebelata mmetụta.Achọpụtala atụmatụ a na nnyefe nke ọgwụ mgbochi ọrịa cancer, ọgwụ nje na ọgwụgwọ ndị ọzọ. Na mgbakwunye na ngwa ngwa ya kpọmkwem, N (ε) -trifluoroacetyl-L-lysine nwekwara ike iji dị ka ihe mgbochi ụlọ maka njikọ nke ogige ndị ọzọ na-arụ ọrụ. .Ọdịdị kemịkal ya pụrụ iche na mmeghachi omume ya na-eme ka ọ bụrụ ihe mmalite na-adọrọ adọrọ ma ọ bụ etiti maka njikọ nke ụmụ irighiri ihe ndị dị mgbagwoju anya, gụnyere ọgwụ, agrochemicals, na material. Otú ọ dị, ọ dị oké mkpa ijikwa N (ε) -trifluoroacetyl-L-lysine na nlezianya. na-eso nchekwa nchekwa kwesịrị ekwesị.A na-atụ aro ka ị rụọ ọrụ na ụlọ nyocha nke ọma ma jiri ngwá ọrụ nchebe onwe onye kwesịrị ekwesị, dị ka uwe aka na enyo nchekwa.Na nchịkọta, N (ε) -trifluoroacetyl-L-lysine bụ ihe bara uru nke lysine nke na-achọta ngwa dị iche iche na peptide. njikọ, nyocha biochemical, nnyefe ọgwụ ezubere iche, na njikọ organic.Ikike ya ichekwa epsilon amino group nke lysine na-enye ohere maka njikọ nke peptide ziri ezi, ebe akụrụngwa kemịkalụ ya gbanwere na-enyere aka ịmụ usoro mgbasa ozi lysine.Mgbe a na-edozi ya nke ọma, N (ε) -trifluoroacetyl-L-lysine na-egosi na ọ bụ ngwá ọrụ bara uru na ngwa sayensị dị iche iche na ụlọ ọrụ mmepụta ihe.