N-Acetyl-L-cysteine CAS: 616-91-1 98% ọcha crystalline ntụ ntụ.
| Nọmba katalọgụ | XD90127 |
| Aha ngwaahịa | N - acetyl-L-cysteine |
| CAS | 616-91-1 |
| Usoro ihe omimi | C5H9NO3S |
| Ibu molekụla | 163.1949 |
| Nkọwa nchekwa | 2 ruo 8 Celsius C |
| Koodu tarifu akwadoro | 29309016 |
Nkọwapụta ngwaahịa
| Ebe mgbaze | 106-112 Celsius C |
| Ntughari pụrụ iche | +21°-+25° |
| Ọla dị arọ | <10ppm |
| Arsenic | <1pm |
| pH | 2.0-2.8 |
| Ọnwụ na ihicha | kacha 1.0% |
| Sulfate | <0.03% |
| Nyocha | 98% nkeji |
| Ígwè | <20ppm |
| Ihe fọdụrụ na mgbanye | kacha .5% |
| Ammonium | <0.02% |
| cl | <0.04% |
| Ọdịdị | White crystalline ntụ ntụ |
| Ọnọdụ Ngwọta | > 98% |
N-Acetyl-L-cysteine bụ amino acid acetylated nwere antioxidant na mucolytic Njirimara.Ihe omume abụọ a egosila N-Acetyl-L-cysteine dị ka ọ dị mkpa na ọgwụgwọ kemịkalụ nke cystic fibrosis, ebe antioxidant / mbelata agwa nke onyinye ahụ na-eme ka njirimara sistemụ redox ahaghị nhata nke CF na njirimara mucolytic nke ogige ahụ na-egbochi. nchikota na mbufụt jikọtara ya na steeti redox a.Dị ka mucolytic, N-Acetyl-L-cysteine na-eje ozi iji kpochapụ agbụ disulfide n'ofe mucoproteins, na-atọpụ na ikpochapụ viscosity nke sputum.N-Acetyl-L-cysteine na-egosi mmemme ekele maka glutathione, ma na-egosipụta ọrụ antioxidant site na arụ ọrụ thiol ha, na egosiri ha abụọ iji chebe nrụgide peroxidative metụtara septic ujo.N-Acetyl-L-cysteine e gosikwara na ọ na-ebute apoptosis na sel anụ ahụ dị nro na-adịghị mma, na-egosi na mkpụrụ ndụ ndị a na-emeghachi omume n'ụzọ dị iche iche na mgbanwe na mbelata-oxidation steeti karịa anụ ahụ ndị ọzọ na-echebekarị site na ọnụnọ nke antioxidants.Mmekọrịta a na-eju anya na mkpụrụ ndụ akwara dị nro na-egosi N-Acetyl-L-cysteine dị ka ntinye aka na-ekwe nkwa maka mgbasa arteriosclerotic nke mkpụrụ ndụ ndị a.
Njirimara kemịkalụ: N-acetyl-L-cysteine white crystalline powder, nwere isi dị ka galik na uto utoojoo.Hygroscopic, soluble na mmiri ma ọ bụ ethanol, nke na-adịghị edozi na ether na chloroform.Ọ bụ acidic na mmiri mmiri ngwọta (pH2-2.75 na 10g/LH2O), mp101-107 ℃Chemicalbook.Ngwaahịa a bụ ihe N-acetylated sitere na cysteine.Ngwakọta ahụ nwere otu sulfhydryl, nke nwere ike mebie njikọ disulfide (-SS-) nke njikọ peptide mucin, si otú a na-atụgharị agbụ mucin n'ime obere peptide nke molekụla, na-ebelata N'ihi viscosity nke mucin, ngwaahịa a bụ mgbaze. ọgwụ maka viscous sputum, purulent sputum na imi iku ume.
Mmekọrịta ọgwụ:
1. A gaghị eji ya na ọgwụ nje penicillin, cephalosporin na tetracycline, n'ihi na nke ikpeazụ nwere ike ghara ịdị irè.
2. Nchikota ma ọ bụ ojiji ọzọ na isoproterenol nwere ike melite mmetụta ọgwụgwọ ma belata mmeghachi omume ọjọọ.
3. Zere kọntaktị na arịa ígwè na roba, oxidants, na oxygen.
Na-eji: ndu reagents, akụrụngwa, thiol (-SH) na molekul nwere ike imebi disulfide yinye (-SS) jikọọ mucin peptide yinye na mucous phlegm.Mucin na-atụgharị Chemicalbook ka ọ bụrụ obere yini peptide molecular, nke na-ebelata viscosity nke sputum;ọ pụkwara imebi eriri DNA na sputum purulent, n'ihi ya, ọ bụghị nanị na ọ na-agbari sputum ọcha viscous kamakwa sputum purulent.
Na-eji: Na nkà mmụta ọgwụ, a na-eji ya dị ka ọgwụ na-agbaze phlegm.Maka nyocha biochemical, a na-eji ya dị ka ihe mgbochi maka mgbaze phlegm na nsị acetaminophen na ọgwụ.
Na-eji: Maka nyocha biochemical, na nkà mmụta ọgwụ, a na-eji ya dị ka ọgwụ na-agbaze phlegm na ọgwụ mgbochi maka nsị acetaminophen.
Na-eji: Biochemical reagents, ọgwụ, ngwaahịa a na-eji dị ka expectorant, nke a na-ekwu na ọ dị mfe ihicha phlegm na mfe ụkwara.Ọ nwere mmetụta ire ere na sputum viscous.Usoro nke ime ihe bụ na otu sulfhydryl dị na usoro ihe omimi nke ngwaahịa a nwere ike imebi njikọ nke disulfide Chemicalbook na mucin polypeptide yinye na sputum mucous, decompose mucin, belata viscosity nke sputum, ma mee ka ọ dị nro ma dị mfe. ụkwara.Ọ dabara maka nnukwu ọrịa iku ume na-adịghị ala ala nke nwere sputum siri ike ma sie ike ịtụ anya, yana ihe mgbaàmà dị egwu nke ihe isi ike na nsị n'ihi igbochi nnukwu phlegm nke nnyapade.
Na-eji: N-acetyl-L-cysteine nwere ike iji dị ka phlegm-dissolving ọgwụ.Ọ dabara adaba maka mgbochi iku ume nke na-akpata nnukwu ihe mgbochi phlegm na-adọrọ adọrọ.Na mgbakwunye, a pụkwara iji ya mee ihe maka nsị nke nsị acetaminophen.N'ihi na ngwaahịa a nwere isi pụrụ iche, ịwe ya nwere ike ịkpata ọgbụgbọ na ọgbụgbọ.Ọ nwere mmetụta na-akpali akpali na traktị iku ume ma nwee ike ịkpata bronchospasm.A na-eji ya na bronchodilators dị ka isoproterenol na ihe na-amịpụta sputum iji chụpụ sputum.O kwesịghị ịdị na kọntaktị na ọla (dị ka Fe, Cu), roba, oxidants, wdg. E kwesịghị iji ya na ọgwụ nje dị ka penicillin, cephalosporin, tetracycline, wdg, ka ọ ghara ibelata mmetụta antibacterial ya.Jiri nlezianya mee ihe na ndị ọrịa nwere ụkwara ume ọkụ.
