Metronidazole Cas: 443-48-1
| Nọmba katalọgụ | XD91888 |
| Aha ngwaahịa | Metronidazole |
| CAS | 443-48-1 |
| Ụdị molekụlala | C6H9N3O3 |
| Ibu molekụla | 171.15 |
| Nkọwa nchekwa | 2-8 Celsius C |
| Koodu tarifu akwadoro | 29332990 |
Nkọwapụta ngwaahịa
| Ọdịdị | White crystalline ntụ ntụ |
| Asay | 99% nkeji |
| Ebe mgbaze | 159-161 Celsius C (ọkụ) |
| Ebe esi nri | 301.12C (atụmatụ siri ike) |
| njupụta | 1.3994 (atụmatụ siri ike) |
| index refractive | 1.5800 (atụmatụ) |
| Fp | 9 ℃ |
| solubility | acetic acid: 0.1M, doro anya, odo na-ada ada |
| pka | pKa 2.62 (H2O, t = 25 ± 0.2, akọwapụtaghị) (Ajighị n'aka) |
| Mmiri Solubility | <0.1 g/100 ml na 20ºC |
Metronidazole bụ ọgwụ a na-ahọrọ maka amebiases, trichomonasis ikpu na trihlomonadic urethritis n'ime ụmụ nwoke, lambliosis, amebic ọnyụnyụ ọbara, na ọrịa anaerobic nke microorganisms na-enwe mmetụta nke ọgwụ ahụ.Ụdị ọgwụ a bụ flagyl, protostat, trichopol, na vagimid.
Metronidazole dị dị ka ọnụ, intravaginal, n'elu, na parenteral nkwadebe.Ọtụtụ ụlọ ọrụ na-arụpụta ya, mana ọ dị naanị site na ndenye ọgwụ.O yighị ka ikpughe gburugburu ebe obibi n'amaghị ama, ma ọ bụrụ na ọ mee, o yighị ka ọ ga-ebute nsi.
A na-eji ya dị ka antibacterial na ọgwụgwọ rosacea.Antiprotozoal (trichomonas).Ọrịa carcinogen nke mmadụ nwere ike ime.
Metronidazole, bụ ọgwụ nje na ọgwụ antiprotozoal.A na-ejikarị agwọ ma ọ bụ gbochie ọrịa sistemu ma ọ bụ mpaghara nke nje bacteria anaerobic kpatara, dị ka ọrịa nje anaerobic na oghere afọ, tract digestive, usoro ọmụmụ nwanyị, akụkụ iku ume nke ala, akpụkpọ anụ na anụ ahụ dị nro, ọkpụkpụ na nkwonkwo, wdg. , ọrịa meningeal, na colitis nke ọgwụ nje na-akpata dịkwa irè.A na-ejikarị tetanus antitoxin (TAT) na-agwọ tetanus.Enwere ike iji ya maka ọrịa anaerobic nke ọnụ.Na October 27, 2017, ndepụta nke carcinogens nke World Health Organisation's International Agency for Research on Cancer bipụtara na mbụ maka ntụnyere, na metronidazole etinyere na ndepụta nke klaasị 2B carcinogens.Na Jenụwarị 2020, ahọpụtara metronidazole n'ime ngalaba nke abụọ nke ndepụta ịzụ ahịa ọgwụ etiti obodo.
Metronidazole bụ ihe kachasị dị irè dị maka ọgwụgwọ ndị mmadụ n'otu n'otu nwere ụdị amebiasis ọ bụla, ma eleghị anya ma e wezụga onye ahụ na-adịghị ahụ anya ma na-aga n'ihu na-ewepụ cysts.Ọnọdụ ahụ chọrọ maka amebicide intraluminal dị irè, dị ka diloxanide furoate, paromomycin sulfate, ma ọ bụ diiodohydroxyquin.Metronidazole na-arụ ọrụ megide cysts eriri afọ na extraintestinal na trophozoites.
Ọ bụ ezie na ejirila quinacrine hydrochloride maka ọgwụgwọ giardiasis, ọtụtụ ndị dọkịta na-ahọrọ metronidazole.Furazolidone bụ nhọrọ ọzọ.
Metronidazole bụ ọgwụ a na-ahọrọ na Europe maka ọrịa nje anaerobic;nchegbu banyere ọrịa carcinogenic nwere ike ime emewo ka a kpachara anya na ojiji ya na United States. N'oge na-adịbeghị anya, a chọpụtala na ọ dị irè n'ịgwọ ọrịa D. medinensis (Guinea worm) na Helicobacter pylori.
A na-ejikwa ya na acne rosacea, balantidiasis na ọrịa Guinea worm.Ọrịa T. vaginalis na-eguzogide ọgwụ a na-emebu chọrọ ọgwụgwọ pụrụ iche.
