L-Histidine Cas: 71-00-1 98.5% kristal ọcha ma ọ bụ ntụ ntụ crystalline
Nọmba katalọgụ | XD90301 |
Aha ngwaahịa | L-Histidine |
CAS | 71-00-1 |
Usoro ihe omimi | C6H9N3O2 |
Ibu molekụla | 155.15 |
Nkọwa nchekwa | Ambient |
Koodu tarifu akwadoro | 29332990 |
Nkọwapụta ngwaahịa
Nyocha | 98.5% nkeji |
Ọdịdị | Kristal ọcha ma ọ bụ ntụ ntụ kristal |
Ọkwa | USP39 |
Ntughari pụrụ iche | +12.6 Celsius ka +14.0 Celsius |
njirimara | Infrared absorption |
pH | 7.0-8.5 |
SO4 | <=0.03% |
Fe | <= 30ppm |
Ọnwụ na ihicha | <=0.2% |
Ihe fọdụrụ na mgbanye | <=0.1% |
Cl | <=0.05% |
Ọla dị arọ (PB) | <=15pm |
Ngwakọta ndị emetụtara | Achọpụtaghị ihe karịrị 0.5% nke adịghị ọcha onye ọ bụla;Achọpụtaghị ihe karịrị 2.0% nke adịghị ọcha niile |
ya quadruplex na-akpụ usoro G-ọgaranya na-ekesa na-ezighi ezi n'ime genome mmadụ.Ọgaranya ha na ndị na-akwalite oncogenic na telomeres ewepụtala mmasị n'ịtụkwasị G-quadruplex (GQ) maka ọgwụgwọ ọrịa kansa.N'ebe a, anyị na-ewepụta nyocha nke ọnụọgụ na nhazi na ike nke GQ na-emepụta usoro nke a tụrụ site na otu fluorescence nke molekul.Tụkwasị na nke a, anyị na-ejikọta ihe ndị a na GQ ezubere iche ligands na G4 resolvase 1 (G4R1) protein njikọ.Nsonaazụ anyị na-egosi na ma loop (na-abụghị G components) ogologo na usoro na-enye aka na nhazi nke GQ.Otu akara molekul ozugbo na-egosi na mpịakọta ike na-adaberekwa na nhazi akaghị.Anyị na-egosipụta na GQ na-eme ka obere ụmụ irighiri ihe, N-methyl mesoporphyrin IX (NMM), analọgụ ya, NMP na protein G4R1 na-ejikọta ọnụ na ngbanwe GQ yiri ya.Nchọpụta anyị na-arụtụ aka na mgbagwoju anya nke mpịachi GQ na-achịkwa site na ogologo akaghị aka na usoro yana ka nkwekọ GQ si ekpebi obere molekul na protein na-ejikọta propensity.