L-Cystin CAS: 56-89-3 99% kristal ọcha ma ọ bụ ntụ ntụ kristal
| Nọmba katalọgụ | XD90322 |
| Aha ngwaahịa | L-cystin |
| CAS | 56-89-3 |
| Usoro ihe omimi | C6H12N2O4S2 |
| Ibu molekụla | 240.30 |
| Nkọwa nchekwa | Ambient |
| Koodu tarifu akwadoro | 29309013 |
Nkọwapụta ngwaahịa
| Ọdịdị | Kristal ọcha ma ọ bụ ntụ ntụ kristal |
| Nyocha | 99% |
| Ọkwa | USP32 |
| Ntughari pụrụ iche | -215° ruo -225° |
| Ọla dị arọ | <0.0015% |
| AS | 1.5ppm kacha |
| SO4 | 0.040% kacha |
| Fe | <0.003% |
| Ọnwụ na ihicha | 0.20% kacha |
| Mwepu na mgbanye | 0.10% kacha |
| Cl | 0.10% kacha |
Ihe owuwu kristal nke carboxypeptidase T (CpT) nwere phenylalanine na arginine substrate analogs - benzylsuccinic acid na (2-guanidinoethylmercapto) succinic acid - kpebisiri ike site na usoro nnọchi molekụla na mkpebi nke 1.57 Å na 1.62 Å iji dokwuo anya profaịlụ profaịlụ sara mbara kpọmkwem. nke enzyme.Ihe fọdụrụ Leu211 na Leu254 na-echekwa (dịkwa na ma carboxypeptidase A na carboxypeptidase B) ka egosiri na ọ bụ ihe nhazi maka nnabata nke mkpụrụ mmiri hydrophobic, ebe Asp263 bụ maka ịnakwere ihe ndị nwere ebubo nke ọma.Mgbanwe nke ndị na-ekpebi ihe ndị a na-agbanwe profaịlụ mkpụrụ: ụdị CpT Leu211Gln na-enweta ụdị carboxypeptidase B, yana ụdị CpT Asp263Asn carboxypeptidase A-dị ka selectivity.Egosiri na Pro248-Asp258 loop na-emekọrịta ihe na Leu254 na Tyr255 ka ọ na-ahụ maka nnabata nke ihe fọdụrụ C-terminal nke mkpụrụ.Mgbakwunye mkpụrụ na mpaghara S1' na-eduga na ngbanwe ligand-dep endent nke akaghị a, yana mmegharị n'akụkụ Leu254 na-eme ka nhazigharị nke ihe fọdụrụ Glu277 dị mkpa maka catalysis.Nke a bụ nghọta ọhụụ n'ime nhọrọ mkpụrụ nke metallocarboxypeptidase nke na-egosipụta mkpa mmekọrịta dị n'etiti mpaghara S1' na etiti catalytic.
