L-Alanine CAS: 56-41-7 99% ọcha crystalline ntụ ntụ
Nọmba katalọgụ | XD90326 |
Aha ngwaahịa | D-Alanine |
CAS | 338-69-2 |
Usoro ihe omimi | C3H7NO2 |
Ibu molekụla | 89.09 |
Nkọwa nchekwa | Ambient |
Koodu tarifu akwadoro | 29224985 |
Nkọwapụta ngwaahịa
Ọdịdị | White crystalline ntụ ntụ |
Nyocha | 98.5 - 101.5% |
Ntughari pụrụ iche | +13.7 ruo +15.1 |
Ọla dị arọ | <0.0015% |
pH | 5.5-7 |
SO4 | <0.03% |
Ọnwụ na ihicha | <0.2% |
Ígwè | <0.003% |
Ihe fọdụrụ na mgbanye | <0.15% |
Nha urughuru | 200um |
Cl | <0.05% |
Ọkwa nke mmetọ organic na-adịgide adịgide | Enweghị mmetọ |
γ-Glutamyltranspeptidases (γ-GTs) na-ekewa γ-glutamyl amide bond nke glutathione ma bufee otu γ-glutamyl n'ime mmiri (hydrolysis) ma ọ bụ amino acid na-anabata (transpeptidation).Enzymes ndị a dị n'ebe nile na-ekere òkè dị mkpa na biosynthesis na mmebi nke glutathione, na xenobiotic detoxification.Ebe a, anyị na-akọ 3Å mkpebi kristal Ọdịdị nke Bacillus licheniformis γ-GT (BlGT) na nke mgbagwoju ya na l-Glu.Ihe owuwu X-ray na-akwado na BlGT bụ nke N-terminal nucleophilic hydrolase superfamily wee kpughee na protein nwere oghere saịtị na-arụ ọrụ meghere dị ka nke akọọrọ maka enzyme homoloous sitere na Bacillus subtilis, mana dị iche na nke a hụrụ maka mmadụ γ-GT na maka γ-GT sitere na microorganisms ndị ọzọ.Data na-egosi na njiko nke l-Glu na-ebute nhazigharị ọdụ C-terminal nke BlGT nnukwu subunit ma kwe ka njirimara nke ụyọkọ nke foduru acid nke nwere ike itinye aka na njirimara nke ion ígwè.T ọrụ nke ndị a residues na conformational kwụsie ike nke BlGT e mụọ site characterizing na autoprocessing, enzymatic ọrụ, chemical na thermal denaturation nke anọ ọhụrụ Ala otu mutants.Nsonaazụ gosiri na nnọchi nke Asp568 na Ala na-emetụta ma nhazi autoprocessing na nkwụsi ike nke protein.