Glutathione belatara Cas: 70-18-8 98-101% doro anya na enweghị agba.
Nọmba katalọgụ | XD90284 |
Aha ngwaahịa | Glutathione belatara |
CAS | 70-18-8 |
Usoro ihe omimi | C10H17N3O6S |
Ibu molekụla | 307.32 |
Nkọwa nchekwa | 2 ruo 8 Celsius C |
Koodu tarifu akwadoro | 29309098 |
Nkọwapụta ngwaahịa
Nyocha | 98% - 101% |
Ọdịdị | White crystalline ntụ ntụ |
Ọkwa | EP 7.0 |
adịghị ọcha A | <0.5% |
adịghị ọcha B | <0.5% |
Ọla dị arọ | <10ppm |
Ọgwụ nje endotoxin | <0.10EU/mg |
adịghị ọcha C | <1.5% |
adịghị ọcha D | <1.0% |
Ọnwụ na ihicha | <0.5% |
Solubility | Na-agbaze kpamkpam n'ime mmiri, soluble ntakịrị na ethanol na methylene chloride |
Ígwè | <10ppm |
Chlorides | <200ppm |
Ọdịdị nke Ngwọta | O doro anya na enweghị agba |
Ntụgharị anya pụrụ iche | -15.5 ruo -17.5 |
Mgbakọta adịghị ọcha | <2.5% |
Ammonium | <200ppm |
Sulfated ntụ | <0.1% |
Sulfates | <300ppm |
adịghị ọcha E | <0.5% |
Mgbanwe protin translational post-translational, dị ka tyrosine phosphorylation, na-achịkwa mmekọrịta protein-protein (PPI) dị oke mkpa maka nhazi mgbaàmà na phenotypes cellular.Anyị gbatịpụrụ sistemu ngwakọ abụọ nke yist guzosiri ike na-eji protein kinase mmadụ maka nyocha nke phospho-tyrosine (pY) dabere na PPI na nnwale ozugbo, nnukwu ụzọ.Anyị chọpụtara 292 kacha ọhụrụ pY-based PPI bụ ndị gosipụtara nkọwapụta dị elu gbasara kinase na protein mmekọrịta ma kwadoo nnukwu akụkụ na nnwale mgbochi mgbochi sitere na mkpụrụ ndụ anụ mammalian.Ihe dị ka otu ụzọ n'ụzọ isii nke mkparịta ụka ka a na-emezi site n'echiche na-ejikọta usoro ahịrị ahịrị amaara ebe ọtụtụ pY-PPI na-agbaziri site na epitopes linear ndị ọzọ ma ọ bụ na-achịkwa site na ụdị njirimara ọzọ.Nyocha netwọkụ gosipụtara na ihe omume nnabata pY na-ejikọta ya na modul protein jikọtara nke ukwuu raara onwe ya nye n'igosipụta na ụzọ uto cell metụtara ọrịa kansa.N'iji nyocha njide, protein na-emejupụta mba na akwụkwọ ọgụgụ phenotypic iji kọwaa mmekọrịta pY dabere na TSPAN2 (tetraspanin 2) na GRB2 ma ọ bụ PIK3R3 (p55γ), anyị na-enye ihe atụ na-egosi na PPI abụọ na-adabere na pY na-ekpebi ụdị ọrịa kansa cellular.