Erythromycin CAS: 114-07-8 99% ọcha crystalline ntụ ntụ
Nọmba katalọgụ | XD90353 |
Aha ngwaahịa | Erythromycin |
CAS | 114-07-8 |
Usoro ihe omimi | C37H67NO13 |
Ibu molekụla | 733.93 |
Nkọwa nchekwa | Ambient |
Koodu tarifu akwadoro | 29415000 |
Nkọwapụta ngwaahịa
njirimara | Ntụnyere ụdị dị iche iche absorption IR na USP RS |
Mmiri | 10% kacha |
Ethanol | 0.5% kacha |
Ihe fọdụrụ na mgbanye | 0.2% kacha |
Nyocha | 99% |
Ntughari pụrụ iche | -71 ° ruo -78 Celsius |
Ọdịdị | White crystalline ntụ ntụ |
Crystallinity | Na-emezu ihe achọrọ |
Erythromycin B | 12.0% kacha |
ErythromycinC | 5.0% kacha |
Oke nke thiocyanate | 0.3% kacha |
Propanol | 0.5% kacha |
N-butyl acetate | 0.5% kacha |
Erythromycin A enol ether | 0.3% kacha |
Ihe ọ bụla metụtara onye ọ bụla | 3.0% kacha |
N'ime ọmụmụ ihe ugbu a, anyị nyochara mmekọrịta nke ndị na-ahụ maka ọgwụ nje na akpụkpọ anụ anọ ụdị lipid nke na-eṅomi akpụkpọ anụ mammalian cell membranes na gram-positive na-adịghị mma ma nyochaa kinetics na-ejikọta site na iji usoro plasmon resonance (SPR) anyị.A na-eme atụmatụ nhọrọ na njirimara njide dị iche iche nke ọgwụ nje na-egbu egbu na akpụkpọ anụ lipid, na nyocha nke kinetic site na ntinye nke ụdị mmeghachi omume nke steeti abụọ.Ahụrụ nyochagharị nke mbied kinetics.Vancomyicn, teicoplanin, erythromycin, na linezolid gosipụtara obere mmekọrịta na akpụkpọ anụ anọ dị na sistemụ SPR.N'aka nke ọzọ, vancomycin analogues gosipụtara mmekọrịta ya na ihe nlereanya lipid membranes na sistemụ SPR.A na-atụle njirimara nhọrọ na nke akọwapụtara nke njikọta nke vancomycin analogues na akpụkpọ anụ lipid dabere na data maka ọrụ nje nje in vitro yana data anyị na njikọ njikọ D-alanyl-D-ala itoolu nke mgbidi sel pentapeptide nke SPR nwetara.Enwere ike nyochaa usoro ọrụ antibacterial megide Staphylococcus aureus na enterococci vancomycin na-eguzogide ọgwụ site na iji njikọ njikọ nke enwetara na usoro SPR anyị.Nsonaazụ na-egosi na enwere ike itinye usoro SPR n'ọtụtụ ebe iji buo amụma njide, dị ka nhọrọ na nkọwapụta, nke ọtụtụ ihe na-egbochi nje na akpụkpọ anụ lipid.