Cyclosporin A CAS: 59865-13-3 White crystalline ntụ ntụ 99%
| Nọmba katalọgụ | XD90346 |
| Aha ngwaahịa | Cyclosporin A |
| CAS | 59865-13-3 |
| Usoro ihe omimi | C62H111N11O12 |
| Ibu molekụla | 1202.61 |
| Nkọwa nchekwa | 2 ruo 8 Celsius C |
| Koodu tarifu akwadoro | 29419000 |
Nkọwapụta ngwaahịa
| Nyocha | 99% |
| Ọdịdị | White crystalline ntụ ntụ |
| Ọkwa | USP 35 |
| adịghị ọcha | Mkpokọta adịghị ọcha: 0.6% kacha, Max Otu adịghị ọcha: 0.2% |
| Ọla dị arọ | 20ppm kacha |
| Acetone | 10ppm |
| Ọnwụ na ihicha | 2.0% kacha |
| Okpomọkụ nchekwa | + 4% |
| Ọdịdị nke Ngwọta | Ngwọta dịka nkọwapụta dị na EPIV |
| Ihe ndị na-agbaze mmanụ mmanụ | 31ppm |
Njirimara: ntụ ntụ ọcha ma ọ bụ na-acha ọcha, enweghị isi na enweghị ụtọ.Ọ na-agbaze ngwa ngwa na methanol, ethanol ma ọ bụ acetonitrile, na-agbaze ngwa ngwa na ethyl acetate, soluble na acetone ma ọ bụ ether, na ọ fọrọ nke nta ka ọ ghara ịsacha ya na mmiri.A na-ekpebi ntụgharị nke ngwaahịa a site na akwụkwọ kemịkal, wee gbazee na methanol iji mee ngwọta nwere 10 mg kwa 1 ml.The kpọmkwem ntụgharị bụ -182° ka -192°.Na-eji: nyocha biochemical.Mgbochi nke ụzọ mgbaàmà nnabata T cell
Ngwaahịa a bụ ụdị immunosuppressant ọhụrụ.Ọ bụ ihe cyclic polypeptide mejupụtara amino acid iri na otu.Ọ na-egbochi ọrụ mgbochi mkparị na nke cell na-enyefeghị n'imebi ụmị ọkpụkpụ yana ibelata ọnụ ọgụgụ mkpụrụ ndụ ọbara ọcha.Nwere ike igbochi ịjụ anụ ahụ a tụgharịrị ma ọ bụ akụkụ Chemicalbook.A na-eji ya na ụlọ ọgwụ maka ntụgharị akụrụ, imeju, ngụgụ na ntugharị obi.Na mgbakwunye, ọ nwere mmetụta ọgwụgwọ ụfọdụ na ọrịa autoimmune, yana schistosomiasis, ịba, ọrịa shuga, AIDS, wdg, yana ihe mgbochi mkpali.
Maka ọgwụgwọ ọrịa leukemia, ọrịa kansa, mkpụgharị akụrụ, ụkwara nta, wdg.
