A na-emepụta ọgwụ mgbochi monoclonal (mAb 8281) kpọmkwem maka njedebe β-galactose (βGal) nke glycosphingolipids (GSL) na glycoproteins sitere na ụmụ oke ejiri ọgwụ mgbochi lipid wepụ si na sel ọhụrụ lymphocytic leukemia (ALL).Immuno-thin Layer chromatography (ITLC) na nyocha asọmpi na ụkpụrụ GSL na-anọpụ iche, shuga n'efu, na neoglycoproteins sịntetik gosipụtara mAb 8281 na-emeghachi omume ike na LacCer, GalCer na Gal-β-O- (CH3) 2S (CH3) 2- CONH- (Gal-β-O-CETE) jikọtara ya na albumin serum bovine (BSA).Sugar penultimate sokwa na njikọta.Mgbochi ahụ anaghị arụ ọrụ na carbohydrates nwere usoro αGal njedebe yana akụkụ njedebe na-enweghị njikọ.Indirect immunoperoxidase staining na eruba cytometry na mAb 8281 gosipụtara ezigbo ntụpọ n'ọtụtụ anụ ahụ, gụnyere akwara dị nro, mucosa eriri afọ, sel B lymph na monocytes.Nyocha ITLC nke ihe mejupụtara GSL nke ọhụrụ B cell neoplasms site na iji mAb 8281 kwadoro ọnụnọ nke lactosylceramide na galactosylceramide na neoplasms nke ọkwa dị iche iche nke ọdịiche.N'ihi nkọwapụta ya maka ihe fọdụrụ carbohydrate βGal, mAb 8281 nwere ike ịba uru na nyocha nhazi na arụmọrụ nke GSL.
