Amphotericin B CAS: 1397-89-3 odo ma ọ bụ oroma ntụ ntụ
| Nọmba katalọgụ | XD90365 |
| Aha ngwaahịa | Amphotericin B |
| CAS | 1397-89-3 |
| Usoro ihe omimi | C47H73NO17 |
| Ibu molekụla | 924.08 |
| Nkọwa nchekwa | 2 ruo 8 Celsius C |
| Koodu tarifu akwadoro | 29415000 |
Nkọwapụta ngwaahịa
| Salmonella | Ihe ọjọọ |
| Acetone | 5000ppm max |
| Ọnwụ na ihicha | 5.0% kacha |
| Nkọwapụta | USP 38 |
| Ethanol | 5000ppm max |
| Ihe fọdụrụ na mgbanye | <3% |
| Ọdịdị | Yellow ma ọ bụ oroma ntụ ntụ |
| Ngụkọta ọnụ ọgụgụ ikuku | ≤ 100CFU/g |
| Escherichia coli | Ihe ọjọọ |
| Nyocha | ≥ 750μg/mg |
A na-eji gel Chitosan-dextran mee ihe dị ka ihe na-egbochi hemostatic na ihe mgbochi mgbe ịwa ahụ endoscopic sinus gasịrị.N'ihi na Staphylococcus aureus biofilms etinyewo aka na recalcitrant rhinosinusitis na-adịghị ala ala, ọmụmụ a chọrọ n'ihu nyocha (i) mgbochi mkpali, (ii) mgbochi biofilm nje bacteria, (iii) mmetụta antiproliferative, na (iv) ihe na-agwọ ọnya nke chitosan na chitosan-dextran gel.Fibroblasts dịpụrụ adịpụ na anụ ahụ imi mmadụ ma jiri ya mee ihe iji chọpụta mmetụta nke chitosan na chitosan-dextran gel na (i) mmụba cell, (ii) ọgwụgwọ ọnya, (iii) mbufụt na omenala fibroblast gbara aka na superantigens S. aureus enterotoxin B (SEB) na toxic shock syndrome toxin (TSST), na (iv) na S. aureus biofilms.Chitosan dị irè nke ukwuu n'ibelata okwu IL-8 mgbe TSST na SEB ịma aka.Chitosan dịkwa irè n'ibelata okwu IL-8 nke fibroblasts na-enweghị mgbagha na-egosi mmetụta mgbochi mkpali ya na fibroblasts na steeti ad iseased.Gel Chitosan-dextran gosipụtara ihe antibiofilm siri ike na 50% (v / v) itinye uche na vitro.Dextran, n'onwe ya, gosipụtara ihe antibiofilm na ntinye 1.25% (w / v).Chitosan, n'onwe ya, belata mmụba nke fibroblasts ruo 82% nke njikwa njikwa na chitosan-dextran gel belatara mmụba nke fibroblasts na 0.04% nke njikwa njikwa.N'ihe gbasara nchịkwa nchịkwa na-enweghị ọgwụgwọ, chitosan-dextran gel na-egbu oge na-egbu oge na-agwọ ọrịa ọnya n'ime awa 48 mbụ nke nnwale ahụ. oge.Chitosan belatara ọkwa IL-8, na-egosi njirimara mgbochi mkpali ya.Chitosan-dextran gel na ọgwụgwọ dextran gosipụtara ihe antibiofilm n'ụdị anyị.
