ACES Cas: 7365-82-4 White crystalline ntụ ntụ 99% N- (Carbamoylmethyl) taurine
Nọmba katalọgụ | XD90108 |
Aha ngwaahịa | ACES (N- (2-Acetamido) -2-aminoethanesulfonic acid) |
CAS | 7365-82-4 |
Usoro ihe omimi | C4H10N2O4S |
Ibu molekụla | 182.2 |
Nkọwa nchekwa | Ambient |
Koodu tarifu akwadoro | 29241900 |
Nkọwapụta ngwaahịa
Ndu | <5ppm |
pH | 3.5-4.5 |
Ọdịnaya Mmiri | <0.5% |
Ígwè | <5ppm |
Ihe fọdụrụ na mgbanye | <0.1% |
Ọdịdị | White crystalline ntụ ntụ |
A260 (mmiri 0.1M) | <0.020 |
A280 (mmiri 0.1M) | <0.010 |
Assay (Titration) na ntọala a mịrị amị | > 99% |
Ebumnuche nke ọmụmụ a bụ iji tụnyere ịdị irè nke valproate na haloperidol n'ibelata ọkwa mkpasu iwe na ndị ọrịa metụtara na ngalaba mberede.Anyị kenyere ndị ọrịa 80 nwere oke iwe ka ha nata ma ọ bụ sodium valproate intravenous (20 mg / kg) ma ọ bụ haloperidol intramuscular (5 mg / 1 ml).A tụrụ mgbakasị ahụ na ntọala na 30 min ka ịgba ọgwụ mbụ ahụ jiri nyocha Agitation-Calmness Evaluation Scale (ACES), Ihe Nleba Dị Mma na Ahụhụ Na-adịghị Mma, na Ọnụ ọgụgụ Omume Agitated.Maka ndị ọrịa 80 a na-emeso ya na sodium valproate, ọnụọgụ ± SD pụtara bụ 1541.5 ± 286 mg (oke 940-2400).Ọnụ ọgụgụ ACES postintervention nke pụtara site na ntọala ruo 30 min mgbe ịgba ọgwụ ọgwụ gasịrị bụ 4.73 (SD = 1.93) maka otu valproate na 5.45 (SD = 2.09) maka otu haloperidol (P = 0.028).Enweghị ọdịiche dị ịrịba ama n'ihe gbasara mgbanwe mgbanwe 30 min mgbe ntinye aka maka akpịrịkpa mgbakasị abụọ ọzọ.Ọnụ ọgụgụ ka ukwuu nke ndị ọrịa nọ na haloperidol nwere mmetụta nkwụsịtụ siri ike (36.2%, P <0.001) na mgbaàmà extrapyramidal (8.7%, P = 0.007) ma e jiri ya tụnyere ìgwè valproate (2.5% maka nkwụsịtụ siri ike, enweghị onye ọrịa maka mgbaàmà extrapyramidal).Nchoputa a na-egosi na n'ime usoro nlekọta ahụike nke psychiatry mberede, valproate intravenous dị irè dị ka haloperidol n'ibelata mkpasu iwe, yana profaịlụ nchekwa ka mma.