Ngwaahịa

7,8-Dimethoxy-1,3-dihydro-2H-3-benzazepin-2-otu bụ ngwakọta nke nwere usoro kemịkalụ dị mgbagwoju anya nke na-achọta ngwa n'akụkụ dị iche iche, gụnyere kemistri ọgwụ na nyocha neuroscience. Otu n'ime isi ihe eji eme ihe a. Ngwakọta dị n'ọhịa kemịkalụ ọgwụ.Ọ na-eje ozi dị ka ngọngọ ụlọ ma ọ bụ n'etiti na njikọ nke ọgwụ nwere ike ọgwụgwọ ngwa.The benzazepinone scaffold dị ugbu a na ogige a na-ahazi dị ka ụfọdụ neurotransmitters na ọgwụ lekwasịrị anya, na-eme ka ọ bụrụ ngwá ọrụ bara uru maka ịmepụta na ịmepụta ogige ọgwụ ọhụrụ.Site n'ịgbanwe usoro nke 7,8-Dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one, ndị na-ahụ maka ọgwụ na-agwọ ọrịa nwere ike ịmepụta ihe ndị na-egosipụta njikọ njikọ dị iche iche na selectivity n'ebe dị iche iche anabata ma ọ bụ enzymes, nwere ike na-eduga na nchoputa. nke novel therapeutic agents.Na mgbakwunye, a mụọla ogige a n'ọhịa nyocha nke neuroscience.Ọdịdị benzazepinone yiri ụfọdụ agonists dopamine receptor, nke bụ ogige ndị na-eme ka ndị na-anabata dopamine na ụbụrụ.Dopamine na-arụ ọrụ dị oke mkpa na nhazi nke ọnọdụ, mmegharị, na usoro ụgwọ ọrụ, na-eme ka ọ bụrụ ebumnuche dị mkpa maka mmepe nke ọgwụ ndị metụtara nsogbu akwara ozi dị ka ọrịa Parkinson na schizophrenia.Site n'ịmụ mmetụta nke 7,8-Dimethoxy-1,3-dihydro-2H-3-benzazepin-2-otu na ihe ndị na-emepụta ya na ndị na-anabata dopamine, ndị ọkà mmụta sayensị nwere ike nweta nghọta na ọrụ nke ndị a na-anabata ya ma nwee ike ịmepụta ọgwụgwọ ọhụrụ maka akwara ozi. Ọnọdụ.Ọzọkwa, 7,8-Dimethoxy-1,3-dihydro-2H-3-benzazepin-2-otu ka enyochakwara maka ọrụ antioxidant na mgbochi mkpali.Nchegbu oxidative na mbufụt bụ ihe na-akpata na ọnọdụ ọrịa dị iche iche, gụnyere ọrịa obi, ọrịa neurodegenerative, na ọrịa kansa.Ndị na-eme nchọpụta enyochala ikike nke ogige ahụ iji mebie radicals free na igbochi usoro mkpali, nke nwere ike inwe mmetụta maka mmepe nke ọgwụgwọ na-elekwasị anya na ọnọdụ ndị a. N'ikpeazụ, 7,8-Dimethoxy-1,3-dihydro-2H-3-benzazepin-2 -otu bụ ngwakọta nwere ọtụtụ ngwa na kemistri ọgwụ na nyocha neuroscience.Usoro kemịkalụ ya pụrụ iche na-eme ka ọ baa uru maka njikọ nke ndị na-achọ ọgwụ, ọkachasị ndị na-achọ ndị na-anabata neurotransmitter.Ọzọkwa, ihe ndị nwere ike ịbụ antioxidant na mgbochi mkpali na-emeghe ohere maka ịmalite ọgwụgwọ maka ọrịa dị iche iche.Ịga n'ihu na-eme nchọpụta nke ogige a na ihe ndị na-emepụta ya nwere ike ime ka nchọpụta dị mkpa na ọganihu dị na ngalaba nke nkà mmụta ọgwụ na neuroscience.