5,6,7,7a-Tetrahydrothieno[3,2-c] pyridine-2(4H) -otu hydrochlorideCAS: 115473-15-9
Nọmba katalọgụ | XD93406 |
Aha ngwaahịa | 5,6,7,7a-Tetrahydrothieno[3,2-c] pyridine-2(4H) -otu hydrochloride. |
CAS | 115473-15-9 |
Ụdị molekụlala | C14H8ClFN2O3 |
Ibu molekụla | 191.67 |
Nkọwa nchekwa | Ambient |
Nkọwapụta ngwaahịa
Ọdịdị | Ọcha ntụ ntụ |
Asay | 99% nkeji |
5,6,7,7a-Tetrahydrothieno [3,2-c] pyridine-2 (4H) -otu hydrochloride, nke a makwaara dị ka riluzole hydrochloride, bụ ọgwụ a na-ejikarị eme ihe na ọgwụgwọ nke amyotrophic lateral sclerosis (ALS), nke a makwaara dị ka ọrịa Lou Gehrig.Ọ bụ ọgwụ ọnụ na-arụ ọrụ site n'ịgbanwe ọkwa nke glutamate, neurotransmitter na-akpali akpali, na ụbụrụ.Riluzole hydrochloride na-eche na ọ na-arụ ọrụ site n'ibelata ntọhapụ glutamate, igbochi glutamate, na igbochi ndị na-anabata glutamate.Ekwenyere na Glutamate na-ekere òkè na ọganihu nke ALS na site n'ịgbanwe ọkwa ya, riluzole hydrochloride nwere ike belata mmebi nke neurons moto ma nwee ike inye aka mee ka ndụ dịkwuo ogologo. enwere ike iji ya na nsogbu akwara ozi ndị ọzọ dị ka ọrịa Alzheimer, multiple sclerosis, na ịda mbà n'obi.Otú ọ dị, a ka na-amụ irè ya n'ọnọdụ ndị a ma chọọ nyocha ọzọ. Dị ka ọgwụ ọ bụla, riluzole hydrochloride nwere ike ịkpata mmetụta.Mmetụta ndị a na-ahụkarị gụnyere ọgbụgbọ, ọgbụgbọ, isi ọwụwa, adịghị ike, na mgbu afọ.Mmetụta adịghị adịkarị ma dị njọ nwere ike ịgụnye nsogbu imeju, mmeghachi ahụ nfụkasị ahụ, na mgbanwe n'ọgụgụ ọbara.Ọ dị mkpa ka onye ọkachamara ahụike kwurịta ihe ize ndụ na uru ọ bụla nwere ike ime tupu ịmalite riluzole hydrochloride.Na njedebe, 5,6,7,7a-Tetrahydrothieno [3,2-c] pyridine-2 (4H) -one hydrochloride, ma ọ bụ riluzole. hydrochloride, bụ ọgwụ eji agwọ ALS site n'ịgbanwe ọkwa glutamate na ụbụrụ.Ọ bụ ezie na ọ dị irè n'ibelata ọganihu nke ALS, ọ nwekwara ike ịkpata mmetụta dị n'akụkụ nke kwesịrị ileba anya.A ka na-enyocha ojiji ya na ọnọdụ akwara ozi ndị ọzọ.