5-Methyluridine CAS: 1463-10-1 99% ọcha ntụ ntụ
Nọmba katalọgụ | XD90567 |
Aha ngwaahịa | 5-Methyluridine |
CAS | 1463-10-1 |
Usoro ihe omimi | C10H14N2O6 |
Ibu molekụla | 258.228 |
Nkọwa nchekwa | 2 ruo 8 Celsius C |
Koodu tarifu akwadoro | 2934999090 |
Nkọwapụta ngwaahịa
Ọdịdị | Ọcha ntụ ntụ |
Nyocha | 99% |
tRNA bụ otu ụdị RNA kachasị emezigharị nke ukwuu, yana mgbanwe dị na tRNA si n'anụ ahụ niile enyochala.N'agbanyeghị ụdị kemịkalụ ha dị iche iche na ọnụnọ ha na tRNA dị iche iche, na-eme n'ebe dị iche iche na tRNA, ụzọ biosynthetic nke ọtụtụ mgbanwe tRNA gụnyere usoro methylation.Nchoputa na nso nso a ekpughere mgbagwoju anya na-enwetụbeghị ụdị ya na usoro mgbanwe nke tRNA, ụkpụrụ na ọrụ ha, na-atụ aro na nucleoside ọ bụla gbanwere na tRNA nwere ike inwe ọrụ nke ya.Agbanyeghị, n'ime osisi, ihe ọmụma anyị gbasara ọrụ mgbanwe tRNA nke onye ọ bụla na otu esi ahazi ha nwere oke.Na ihuenyo mkpụrụ ndụ ihe nketa emere iji chọpụta ihe na-achịkwa nguzogide ọrịa na ịgbalite ihe nchebe na Arabidopsis, anyị chọpụtara SUPPRESSOR OF CSB3 9 (SCS9).Nsonaazụ anyị na-ekpughe SCS9 na-etinye koodu tRNA methyltransferase nke na-edozi 2'-O-ribose methylation nke ụdị tRNA ahọpụtara na antico don loop.Mgbanwe ndị a nke SCS9 na-eme ka tRNA na-eme ka ọ dịkwuo mma n'oge ọrịa na-efe efe na nje pathogen Pseudomonas syringae DC3000, na enweghị mgbanwe tRNA dị otú ahụ, dị ka a na-ahụ na scs9 mutants, na-emebi ihe mgbochi osisi megide otu pathogen na-emetụtaghị salicylic acid (SA). ụzọ nke na-achịkwa nzaghachi mgbochi osisi.Nsonaazụ anyị na-akwado ihe atụ nke na-enye mkpa njikwa nke ụfọdụ mgbanwe tRNA maka ịgbalite nzaghachi mgbochi dị irè na Arabidopsis, ya mere na-agbasawanye nkọwa nke ihe ndị dị mkpa maka nzaghachi ọrịa nke ọma.