4-Amino-1- ((2R,4S,5R) -4-hydroxy-5- (hydroxymethyl) tetrahydrofuran-2-yl) pyrimidin-2 (1H) -otu Cas: 951-77-9
| Nọmba katalọgụ: | XD90580 |
| Cas: | 951-77-9 |
| Ụdị molekụla: | C9H13N3O4 |
| Ibu Molecular: | 227.22 |
| Nnweta: | Dị na ngwaahịa |
| Ọnụ ahịa: | |
| Nkwakọ ngwaahịa: | 1g USD10 |
| Ngwungwu nnukwu: | Rịọ Quote |
Nkọwapụta ngwaahịa
| Ọdịdị | White crystalline ntụ ntụ |
| Nyocha | 99% |
| Ebe mgbaze | 196°C -200°C |
Thymidine phosphorylase (TP, EC 2.4.2.4) ghọtara nhazi nke mkpụrụ ahụ na nkọwa dị elu, site na ma isi na ribosyl moieties.Ndochi nke 3'-OH nke thymidine ji TP mee mmetụta nke ọma na ọrụ catalytic ya.Ntughari nke pyrimidine nucleosides nwere akụkụ ntọala gbanwetụrụ gaa na ụdị 1-phosphate dabara adaba.Ọrụ ha na-ahapụ ahụ belatara site na mmụba nke aromaticity nke pyrimidine base moiety, n'ihi na ọ na-esiwanye ike na-eme ka ntọala amino acid dị na mpaghara ahụ na saịtị nọ n'ọrụ.Ndochi nke otu 3' na 5' na-arụ ọrụ na-achọ ibelata ọnụego mmeghachi omume yana ngbanwe pasent na TP.Karịsịa ribosyl 3' hydroxyl otu dị mkpa n'ụzọ nhazi maka njikọ nke mkpụrụ osisi site na enzyme.Nyocha nke kinetic gosipụtara n'ụzọ doro anya ụkpụrụ K(m) dị elu na V (max) dị ala na iji hydrogen dochie otu 3' hydroxyl.
