Ngwaahịa

2-Pyrrolidinecarboxamide, 1- (2-chloroacetyl) -, (2S) - bụ ngwakọta nke nwere ngwa dị iche iche n'ọhịa nke kemịkalụ organic na nyocha ọgwụ.Ngwakọta a, nke a makwaara dị ka (2S) -2-Pyrrolidinecarboxamido-2-chloroacetic acid amide, na-egosipụta atụmatụ nhazi nke na-eme ka ọ dị mma maka ụfọdụ mmeghachi omume kemịkal na ọmụmụ ihe ndụ.Na njikọ nke organic, (2S) -2-Pyrrolidinecarboxamido-2-chloroacetic Enwere ike iji acid amide mee ihe dị ka ihe mmalite ma ọ bụ etiti na njikọ nke ụmụ irighiri ihe dị mgbagwoju anya.Ọdịdị chiral ya, ya na nhọpụta (2S), na-egosi na o nwere nhazi atọ dị iche iche nke atọ nwere ike imetụta stereochemistry na njirimara nke usoro ya.Ngwongwo a na-eme ka ọ bụrụ ihe bara uru n'ichepụta na mmepụta nke ọgwụ ọhụrụ na ogige ọgwụ. N'ime ụlọ ọrụ ọgwụ, (2S) -2-Pyrrolidinecarboxamido-2-chloroacetic acid amide ka amụrụ maka ikike ya dị ka onye na-egbochi enzymes ma ọ bụ protein na-etinye aka na ya. kpọmkwem usoro ndu ndu.Ụfọdụ nnyocha lekwasịrị anya na ngwa ya dị ka onye na-egbochi ụfọdụ proteases, nke bụ enzymes na-ekere òkè na usoro dị iche iche nke anụ ahụ.Site n'ichebe nhọrọ na igbochi proteases ndị a, enwere ike nweta mmetụta ọgwụgwọ dị mkpa. Ọzọkwa, (2S) -2-Pyrrolidinecarboxamido-2-chloroacetic acid amide nwere ike bụrụ ihe mmalite maka njikọ nke peptide analogs ma ọ bụ mimetics.Ụmụ irighiri ihe ndị a nwere ike iṅomi nhazi na ọrụ nke peptides na-emekarị, si otú a na-emetụta ebumnuche ma ọ bụ ihe omume ụfọdụ.Ihe analogues dị otú ahụ nwere ike ịnwe ngwa ngwa na mmepe nke ọgwụ maka ọgwụgwọ ọrịa dị iche iche, gụnyere ọrịa cancer, ọrịa metabolic, na ọnọdụ akwara ozi. na nyocha ụlọ nyocha ma akwadoghị maka ojiji ụlọ ọgwụ.A ka na-enyocha ngwa ndị nwere ike ịgwọ ọrịa nke ogige ahụ, a na-achọkwa nyocha ọzọ iji chọpụta nchekwa ya na ịdị irè ya n'ime ụmụ mmadụ. N'ikpeazụ, (2S) -2-Pyrrolidinecarboxamido-2-chloroacetic acid amide bụ ngwakọta nke nwere ngwa dị iche iche na nhazi organic na nyocha ọgwụ.Ọdịdị chiral ya na ikike nke igbochi ụfọdụ enzymes ma ọ bụ protein na-eme ka ọ baa uru maka mmepụta ọgwụ ọhụrụ na usoro ọgwụgwọ.Ọ bụ ezie na ojiji ya na nyocha ụlọ nyocha na-egosi nkwa, nyocha ọzọ dị mkpa iji ghọta nke ọma ikike ya na ngwa ụlọ ọgwụ.