Ngwaahịa

Ngwakọta 2- ({(5S) -2-oxo-3-[4- (3-oxomorpholin-4-yl) phenyl] -1,3-oxazolidin-5-yl}methyl) -1H-isoindole-1, 3 (2H) -dione bụ ihe mgbagwoju anya organic molecule nke nwere ngwa ngwa n'ọhịa nke ọgwụ na ọgwụ ọgwụ. Ọnụnọ nke isi nke isoindole na-egosi na ogige a nwere atụmatụ nhazi nke dị mkpa na ihe ndị dị ndụ na-ahụ maka ihe ndị dị ndụ.A na-akọ na ihe ndị na-emepụta isoindole nwere ụdị ọgwụ dị iche iche, gụnyere ọgwụ mgbochi, mgbochi mkpali, na ọrụ mgbochi.A na-eji Oxazolidinones mee ihe dị ka ihe dị mkpa na ọgwụ nje, karịsịa megide nje bacteria na-eguzogide ọgwụ.Nke a na-egosi na ogige ahụ nwere ike inwe ike dị ka onye na-ahụ maka nje bacteria. Ọnụnọ nke morpholinone moiety, nke 4- (3-oxomorpholin-4-yl) phenyl na-anọchi anya ya, na-agbakwụnye mgbagwoju anya n'iji ihe eji eme ihe.Ewebatala Morpholines n'ọtụtụ ebe n'ime ogige ọgwụ n'ihi ikike ha nwere imekọrịta ihe na ebumnuche ndu dị iche iche.Otu oxo dị na morpholinone nwere ike ịkwalite mmekọrịta nke ogige ahụ na ebumnuche ụfọdụ, na-eme ka ọ bụrụ ngọngọ ụlọ bara uru na nchọpụta ọgwụ na mmepe.The 2-oxo-3-[4- (3-oxomorpholin-4-yl) phenyl] - Otu 1,3-oxazolidin-5-yl, nke a na-ejikọta na isi nke isoindole, na-emepụta ebe bụ isi na-arụ ọrụ nke ogige ahụ.Ọdịdị kemịkal dị iche iche nke otu a na-egosi na ọ nwere ike inwe mmekọrịta ya na ihe ndị dị ndụ dị ka enzymes ma ọ bụ ndị na-anabata ya. N'ozuzu, dabere na njirimara nhazi nke ogige ahụ, ọ nwere ike igosi ihe omume ọgwụ na antibacterial, mgbochi mkpali, na mpaghara ndị ọzọ nwere ike ịgwọ ọrịa.Otú ọ dị, ọ ga-adị mkpa ka a chọpụta kpọmkwem ihe eji eme ya na usoro ihe omume ya site na nyocha ndị ọzọ, gụnyere in vitro na in vivo tests, iji chọpụta ịdị irè ya na profaịlụ nchekwa. N'ikpeazụ, ogige 2- ({(5S) -2-oxo -3-[4- (3-oxomorpholin-4-yl) phenyl] -1,3-oxazolidin-5-yl}methyl -1H-isoindole-1,3 (2H) -dione na-egosi nkwa na ngalaba ọgwụ. na pharmaceuticals n'ihi mgbagwoju usoro ya na ike pharmacological Njirimara.Nchọpụta n'ọdịnihu dị mkpa iji nyochaa kpọmkwem ojiji ya, ngwa ọgwụgwọ nwere ike, yana n'ozuzu arụmọrụ.