2- (3,5-Dimethyl-4- (2- (pyrrolidin-1-yl) ethoxy) phenyl) -5,7-dimethoxyquinazolin-4 (3H) -otu Cas: 1044871-04-6
Nọmba katalọgụ | XD90961 |
Aha ngwaahịa | 2- (3,5-Dimethyl-4- (2- (pyrrolidin-1-yl) ethoxy) phenyl) -5,7-dimethoxyquinazolin-4 (3H) -otu. |
CAS | 1044871-04-6 |
Usoro ihe omimi | C24H29N3O4 |
Ibu molekụla | 423.5 |
Nkọwa nchekwa | |
Koodu tarifu akwadoro |
Nkọwapụta ngwaahịa
Ọdịdị | |
Nyocha | |
Bebe mmanu mmanu | 612.6± 65.0 °C(buru amụma) |
Njupụta | 1.25±0.1 g/cm3 (buru amụma) |
Ọnụọgụ acidity | (pKa) 9.54± 0.20 (buru amụma) |
RVX-297 bụ onye nwere ike dị ukwuu, onye na-emechi ọnụ na-arụ ọrụ BET nhọrọ maka BD2.IC50s nke RVX-297 maka BRD2(BD2), BRD3(BD2), na BRD4(BD2) bụ 0.08, 0.05, na 0.02 μM, n'otu n'otu.RVX-297 na-egbochi okwu nke mkpụrụ ndụ mkpali na-egbu egbu dị iche iche.Ịdị irè nke RVX-297 na ụdị preclinical nke nnukwu mbufụt na autoimmunity.
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