Ngwaahịa

1-Methyl-4-pyrazole boronic acid pinacol ester bụ ngwakọta kemịkalụ nke na-arụ ọrụ dị oke mkpa na ngalaba nke kemịkalụ organic na nchọpụta ọgwụ.O nwere moiety boronic acid, nke na-eme ka ọ bụrụ ihe mgbochi dị mkpa maka ịmepụta ụmụ irighiri ihe dị iche iche.A na-ejikarị ya eme ihe dị ka ihe mmalite ma ọ bụ etiti na njikọ nke ogige ọgwụ.A maara acid Boronic maka ikike ha ịmepụta ogige kwụsiri ike na ụfọdụ enzymes, karịsịa proteases.Ngwongwo a na-eme ka ha bụrụ ngwaọrụ dị mma maka ịmepụta ndị na-egbochi enzyme nke nwere ike ịhọrọ ụdị ọrịa dị iche iche.Site na itinye pyrazole moiety n'ime boronic acid, ihe na-esi na ya pụta na-egosiputa njikọ chiri anya na nhọrọ n'ebe enzyme ezubere iche.Nke a na-eme 1-Methyl-4-pyrazole boronic acid pinacol ester ka ọ bụrụ ngọngọ ụlọ bara uru maka mbọ nchọpụta ọgwụ na-elekwasị anya na ọrịa ndị sitere na protease dị ka ọrịa cancer, mbufụt, na nje nje. Na mgbakwunye, boronic acid na 1-Methyl-4-pyrazole boronic acid. pinacol ester nwere ike nweta mmeghachi omume kemịkalụ dị iche iche, dị ka mmeghachi omume njikọta nke Suzuki-Miyaura na mmeghachi omume Heck.Mmeghachi omume ndị a na-enye ohere ka e guzobe nke carbon-carbon bond, na-eme ka njikọ nke usoro ihe ndị dị mgbagwoju anya.Otu pyrazole na-agbakwụnyekwu ụdị dị iche iche na ịrụ ọrụ na ogige ndị a na-emepụta, na-eme 1-Methyl-4-pyrazole boronic acid pinacol ester ka ọ bụrụ reagent dị iche iche na nhazi nke organic. Ọzọkwa, 1-Methyl-4-pyrazole boronic acid pinacol ester egosila ike na mmepe nke ihe ndị sitere na boron.Otu boronic acid nwere ihe pụrụ iche nke na-enyere ya aka isonye na nhazi nke onwe ya, na-eduga n'ịmepụta usoro supramolecular.Achọpụtala ikike a n'ihe gbasara sayensị ihe iji mepụta ihe ndị na-arụ ọrụ, dị ka gels, fim, na nanoparticles, nke nwere ike ịchọta ngwa na ngwá electronic, catalysis, na nnyefe ọgwụ.Na nchịkọta, 1-Methyl-4-pyrazole boronic acid. pinacol ester bụ ihe dị iche iche nwere ọtụtụ ngwa.Ọrụ boronic acid ya na-enye ohere maka njikọ nke ụmụ irighiri ihe ndị dị mgbagwoju anya, na-eme ka ọ bụrụ ngọngọ ụlọ dị mkpa na nchọpụta ọgwụ na njikọ organic.Na mgbakwunye, akụrụngwa ya pụrụ iche na-enyere aka imepụta ihe supramolecular nwere ngwa nwere ike na mpaghara dị iche iche.N'ozuzu, ọdịdị ya dị iche iche na-eme ka 1-Methyl-4-pyrazole boronic acid pinacol ester bụrụ ngwá ọrụ bara uru maka ndị nchọpụta na usoro sayensị dị iche iche.